Evidence map›Paper›PMID 41573190›Full record

ArticleStroke (Hoboken, N.J.)2025

PFO-ACCESS: Augmenting Communications for Medical Care or Closure in the Evaluation of Patients With Stroke With Cardiac Shunts.

Yasaman Pirahanchi, Benjamin Shifflett, Ehtisham Mahmud, Stefanie Brennan, Dawn M Meyer, Melissa Mortin, Lovella Hailey, Jeffrey Bowers, Vikas Ravi, Julián Carrión and 5 more

Abstract read
In one paragraph

Article in Stroke (Hoboken, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yasaman PirahanchiNeurosciences University of California San Diego CA.
Benjamin ShifflettNeurosciences University of California San Diego CA.
Ehtisham MahmudCardiovascular Medicine University of California San Diego CA.
Stefanie BrennanCardiovascular Medicine University of California San Diego CA.
Dawn M MeyerNeurosciences University of California San Diego CA.
Melissa MortinNeurosciences University of California San Diego CA.
Lovella HaileyNeurosciences University of California San Diego CA.
Jeffrey BowersNeurosciences University of California San Diego CA.
Vikas RaviNeurosciences University of California San Diego CA.
Julián CarriónNeurosciences University of California San Diego CA.
Reza BavarsadNeurosciences University of California San Diego CA.
Kunal AgrawalNeurosciences University of California San Diego CA.
Royya ModirNeurosciences University of California San Diego CA.
Thomas HemmenNeurosciences University of California San Diego CA.
Brett C MeyerNeurosciences University of California San Diego CA.ORCID https://orcid.org/0000-0002-2877-1187

Funding

San Diego StrokeNet Regional Coordinating CenterU24NS107225 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BRETT C MEYER · 2018 to 2026
$2.4M
NINDS NIH HHS U24 NS107225
6 · The paper itself

Abstract

Background: Patent foramen ovale (PFO) contributes to a quarter of embolic strokes of undetermined source. Although the benefit of PFO closure in selected patients has been demonstrated, our system workflow still resulted in a low rate of PFO evaluation for closure. The aim of the PFO-ACCESS (Augmenting Communications for Medical Care or Closure in the Evaluation of Stroke Patients With Cardiac Shunts) program (which included implementation of the Viz.ai PFO-specific communications module) was to determine if there was any change in PFO management due to improved communication between stroke and interventional cardiology teams. Methods: In this quality improvement project, we compared pre-PFO ACCESS (December 2022-November 2023) to post-PFO ACCESS periods (November 2023-June 2024) regarding PFO evaluations. The Viz.ai PFO module was implemented for the stroke and interventional cardiology teams without other workflow changes. Key performance indicators included referral frequency, PFO closure rates, and referral time intervals. Statistical comparisons utilized Mann-Whitney Results: The postimplementation period noted a 492% PFO referral increase (11 versus 38,65 [annualized]; Conclusion: The PFO-ACCESS program with Viz.ai PFO module use resulted in a 492% increase in PFO referrals due to enhanced communication and efficiency in managing PFO-related stroke cases. Though the increased number of referrals and closures were observed, the PFO closure percentage of total referred cases showed a marked but nonsignificant decrease indicating selective case management. The higher number of PFO closures shows that more patients are indeed appropriate for PFO closure consideration. Future efforts should focus on expanding outpatient use and increasing provider education to optimize PFO management.

Indexed as

AIclosurecommunicationPFOshuntstrokeViz.ai

Identifiers

PMID41573190
PMCPMC12671635

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.