ArticleStroke (Hoboken, N.J.)2025
Endovascular Thrombectomy Versus Best Medical Management in Patients With Large Vessel Occlusion Stroke Presenting Beyond 24 Hours: Results From the TRACK-LVO Late Multicenter Cohort.
Article in Stroke (Hoboken, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- The efficacy and safety of endovascular treatment for acute ischemic progressive stroke beyond 24 h.BMC neurology · 2026Article
- 3-6-24 Anterior Circulation Large Vessel Occlusion-Stroke Screening Rule: A Simple and Feasible Framework.Annals of Indian Academy of Neurology · 2026Article
- A treatment-response framework for interpreting endovascular thrombectomy evidence: established practice, boundary expansion and unresolved frontiers.Frontiers in neurology · 2026Review
- Outcomes of Endovascular Treatment in Patients With Vertebrobasilar Artery Occlusion Beyond 24 Hours.JAMA network open · 2025Article
Corrections and comments
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Authors and funding
18 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe efficacy and safety of endovascular thrombectomy (EVT) performed beyond 24 hours from the last known well remain uncertain. This study aims to investigate the potential benefits of EVT versus best medical management (BMM) beyond 24 hours.
methodsTRACK-LVO Late (Late Triage of Patients Presenting Beyond 24 Hours With Acute Ischemic Stroke Due to Large Vessel Occlusions) is an ongoing, multicenter, prospective cohort study. A total of 410 individuals met the inclusion and exclusion criteria and were included in the cohort analyses from 2018 to 2024. The primary outcome was functional independence, defined as a modified Rankin Scale score of 0-2 at 90 days. Safety outcomes included all-cause mortality within 90 days and symptomatic intracranial hemorrhage. A propensity score analysis was conducted to adjust for baseline imbalances. The association between treatment and primary outcome/safety outcomes was assessed using logistic regression, adjusted for age, sex, National Institutes of Health Stroke Scale score, premorbid modified Rankin Scale score, occlusion sites, and time from onset to admission.
resultsAmong the 410 patients, 209 were in the EVT group and 201 in the BMM group. The EVT group showed higher odds of functional independence in the propensity score-matched cohort (adjusted odds ratio, 4.13 [95% CI, 2.42-7.05];
conclusionEVT performed after 24 hours from the last known well was associated with higher rates of functional independence compared with BMM and demonstrated acceptable safety. High-quality randomized trials are needed to further compare EVT and BMM beyond 24 hours from the last known well.
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