Evidence map›Paper›PMID 41573182›Full record

ArticleStroke (Hoboken, N.J.)2025

How Good Are Neurologists? A Diagnostic Accuracy Study on the Performance of Neurologists in the Emergency Room.

Christoph J Schankin, Bianca-Violeta Popa-Todirenchi, Anne-Sophie Eich, Mattia Branca, Aikaterini Galimanis, Adrian Scutelnic, Martina B Goeldlin, Morin Beyeler, Aristomenis Exadaktylos, Nebiyat Belachew and 7 more

Abstract read
In one paragraph

Article in Stroke (Hoboken, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Christoph J SchankinDepartment of Neurology Inselspital Bern University Hospital and University of Bern Bern Switzerland.
Bianca-Violeta Popa-TodirenchiDepartment of Neurology Inselspital Bern University Hospital and University of Bern Bern Switzerland.
Anne-Sophie EichDepartment of Neurology Inselspital Bern University Hospital and University of Bern Bern Switzerland.
Mattia BrancaCTU Bern University of Bern Bern Switzerland.
Aikaterini GalimanisDepartment of Neurology Inselspital Bern University Hospital and University of Bern Bern Switzerland.
Adrian ScutelnicDepartment of Neurology Inselspital Bern University Hospital and University of Bern Bern Switzerland.
Martina B GoeldlinDepartment of Neurology Inselspital Bern University Hospital and University of Bern Bern Switzerland.
Morin BeyelerDepartment of Neurology Inselspital Bern University Hospital and University of Bern Bern Switzerland.
Aristomenis ExadaktylosDepartment of Emergency Medicine Inselspital Bern University Hospital and University of Bern Bern Switzerland.
Nebiyat BelachewInstitute of Diagnostic and Interventional Neuroradiology Inselspital University Hospital and University of Bern Bern Switzerland.
Mirjam R HeldnerDepartment of Neurology Inselspital Bern University Hospital and University of Bern Bern Switzerland.
Johannes KaesmacherInstitute of Diagnostic and Interventional Neuroradiology Inselspital University Hospital and University of Bern Bern Switzerland.
Thomas R MeinelDepartment of Neurology Inselspital Bern University Hospital and University of Bern Bern Switzerland.
Heinrich P MattleDepartment of Neurology Inselspital Bern University Hospital and University of Bern Bern Switzerland.
Simon JungDepartment of Neurology Inselspital Bern University Hospital and University of Bern Bern Switzerland.
Marwan El-KoussyInstitute of Diagnostic and Interventional Neuroradiology Inselspital University Hospital and University of Bern Bern Switzerland.
Urs FischerDepartment of Neurology Inselspital Bern University Hospital and University of Bern Bern Switzerland.ORCID https://orcid.org/0000-0003-0521-4051

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In people with suspected stroke the first assessment occurs under time pressure in the emergency department and is based solely on clinical information. Working hypotheses include mechanism and localization of the clinical deficit on imaging. To assess the performance of neurologists in such situation, we investigated the accuracy with which board-certified neurologists make the correct diagnosis based solely on clinical information. Methods: In this prospective diagnostic accuracy study done at an emergency department of a university hospital, neurologists had to commit themselves to a diagnosis in people with suspected acute stroke. The main analysis was the accuracy with which they distinguished vascular from nonvascular causes using the discharge diagnosis as a reference. Secondary analyses included the distinction of ischemic from hemorrhagic strokes, and the accuracy with which the lesion location and site of vessel occlusion were identified. The performance of neurologists was also compared to residents and medical students. Results: Of 800 people with suspected stroke, 567 (71%) had a vascular (508 ischemic stroke or transient ischemic attack and 59 hemorrhagic stroke) and 233 (29%) had a nonvascular disorder (72 seizures, 33 migraine auras, 12 functional neurological disorders, and 116 other diseases). Vessel occlusion was found in 227 of 410 people with ischemic stroke. Neurologists identified vascular origin with an accuracy of 0.86 (95% CI: 0.83-0.89), a sensitivity of 0.93 (0.90-0.95), and a specificity of 0.66 (0.58-0.73). The accuracy to identify ischemia compared with hemorrhage was 0.91 (0.87-0.93). Neurologists' accuracy to predict the presence of vessel occlusion was 0.66 (0.61-0.71), of exact lesion location was 42%, and of the affected blood vessel 57%. Conclusion: In people with acute neurological deficits, the accuracy with which neurologists identify vascular origin is high and depends on neurological education. Experienced physicians should be involved early in the management of people with "code stroke."

Indexed as

accuracyclinical assessmentemergencystroke

Identifiers

PMID41573182
PMCPMC12671641

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.