Evidence map›Paper›PMID 41573121›Full record

ArticleChemical science2026

Abiotic formation of nitrile precursors to amino acids and nucleobases in interstellar ice analogues.

Jia Wang, Shiori Inada, Chaojiang Zhang, Joshua H Marks, Zesen Wang, Alexandre Bergantini, Mason McAnally, André K Eckhardt, Ralf I Kaiser

Abstract read
In one paragraph

Article in Chemical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jia WangW. M. Keck Research Laboratory in Astrochemistry, University of Hawaii at Manoa Honolulu Hawaii 96822 USA ralfk@hawaii.edu.ORCID https://orcid.org/0000-0002-3795-8699
Shiori InadaW. M. Keck Research Laboratory in Astrochemistry, University of Hawaii at Manoa Honolulu Hawaii 96822 USA ralfk@hawaii.edu.
Chaojiang ZhangW. M. Keck Research Laboratory in Astrochemistry, University of Hawaii at Manoa Honolulu Hawaii 96822 USA ralfk@hawaii.edu.
Joshua H MarksW. M. Keck Research Laboratory in Astrochemistry, University of Hawaii at Manoa Honolulu Hawaii 96822 USA ralfk@hawaii.edu.
Zesen WangW. M. Keck Research Laboratory in Astrochemistry, University of Hawaii at Manoa Honolulu Hawaii 96822 USA ralfk@hawaii.edu.
Alexandre BergantiniW. M. Keck Research Laboratory in Astrochemistry, University of Hawaii at Manoa Honolulu Hawaii 96822 USA ralfk@hawaii.edu.ORCID https://orcid.org/0000-0003-2279-166X
Mason McAnallyW. M. Keck Research Laboratory in Astrochemistry, University of Hawaii at Manoa Honolulu Hawaii 96822 USA ralfk@hawaii.edu.ORCID https://orcid.org/0009-0000-7799-9914
André K EckhardtLehrstuhl für Organische Chemie II, Ruhr-Universität Bochum Bochum 44801 Germany Andre.Eckhardt@ruhr-uni-bochum.de.ORCID https://orcid.org/0000-0003-1029-9272
Ralf I KaiserW. M. Keck Research Laboratory in Astrochemistry, University of Hawaii at Manoa Honolulu Hawaii 96822 USA ralfk@hawaii.edu.ORCID https://orcid.org/0000-0002-7233-7206

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amino acids and the five canonical nucleobases have been identified in carbonaceous meteorites such as Murchison and Murray; however, their formation mechanisms under interstellar conditions have remained largely elusive. Here, we report the synthesis of biorelevant nitriles, key precursors to amino acids and nucleobases, in low-temperature interstellar model ices composed of hydrogen cyanide (HCN) irradiated with galactic cosmic ray proxies in the form of energetic electrons. Ammonia (NH

Identifiers

PMID41573121
PMCPMC12820785

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.