Evidence map›Paper›PMID 41573099›Full record

ArticleBlood vessels, thrombosis & hemostasis2026

A transgenic mouse model for reticulated platelet detection reveals expansion after myocardial ischemia/reperfusion.

Muataz Ali Hamad, Nancy Schanze, Krystin Krauel, Achim Lother, Stefanie Perez-Feliz, Pia Iaconianni, Mark Zurek, Lama Almushkab, Josef Madl, Marie A Hollenhorst and 3 more

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Article in Blood vessels, thrombosis & hemostasis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Muataz Ali HamadDepartment of Cardiology and Angiology, Heart Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Nancy SchanzeDepartment of Cardiology and Angiology, Heart Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Krystin KrauelDepartment of Cardiology and Angiology, Heart Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Achim LotherInstitute of Experimental and Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Stefanie Perez-FelizInstitute for Experimental Cardiovascular Medicine, University Heart Center Freiburg - Bad Krozingen, Medical Faculty and Medical Center, University of Freiburg, Freiburg, Germany.
Pia IaconianniInstitute for Experimental Cardiovascular Medicine, University Heart Center Freiburg - Bad Krozingen, Medical Faculty and Medical Center, University of Freiburg, Freiburg, Germany.
Mark ZurekDepartment of Cardiology and Angiology, Heart Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Lama AlmushkabDepartment of Cardiology and Angiology, Heart Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Josef MadlInstitute for Experimental Cardiovascular Medicine, University Heart Center Freiburg - Bad Krozingen, Medical Faculty and Medical Center, University of Freiburg, Freiburg, Germany.
Marie A HollenhorstDepartment of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Peter KohlInstitute for Experimental Cardiovascular Medicine, University Heart Center Freiburg - Bad Krozingen, Medical Faculty and Medical Center, University of Freiburg, Freiburg, Germany.
Thomas G NührenbergDepartment of Cardiology and Angiology, Heart Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Daniel DuerschmiedDepartment of Cardiology, Haemostaseology, and Medical Intensive Care, Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reticulated platelets are newly formed, RNA-rich platelets with heightened reactivity. Although elevated levels are observed after myocardial ischemia/reperfusion injury, their functional contributions to postischemic pathology remains poorly defined. We aimed to determine whether reticulated platelets actively contribute to inflammation and repair following myocardial ischemia and reperfusion, rather than serving solely as biomarkers of platelet turnover. We generated

Identifiers

PMID41573099
PMCPMC12820585

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.