ArticleInternational journal of ophthalmology2026
Insights into risk factors and interactive effects on epiretinal membrane development from the National Health and Nutrition Examination Survey.
Article in International journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
aimTo assess risk factors for epiretinal membranes (ERM) and examine their interactions in a nationally representative U.S. dataset.
methodsData from the 2005-2008 National Health and Nutrition Examination Survey (NHANES) were analyzed, a nationally representative U.S. dataset. ERM was identified
resultsTotally 3925 participants were analyzed. Older age, eye surgery, and refractive errors were significantly associated with ERM. Compared to those under 65y, the odds ratio (OR) for ERM was 3.08 for ages 65-75y (
conclusionERM is significantly associated with aging, eye surgery, and refractive errors. The interaction between eye surgery and refractive error modifies ERM risk and highlights the importance of considering combined effects in clinical risk assessments. These findings may help guide individualized ERM risk assessment that may inform personalized approaches to ERM prevention and management.
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