Evidence map›Paper›PMID 41572747›Full record

ReviewCurrent medical imaging2026

Clinical Application of Magnetic Resonance Imaging in the Diagnosis of NAFLD

Jifei Deng, Shizhao Ou, Lijuan Lai, Derek Corica, Lijun Dong, Yujiang Fang, Guojun Song

Erratum issuedAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current medical imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Jifei DengDepartment of Radiology, Nanhua Hospital Affiliated to Nanhua University, Hengyang, China.
Shizhao OuDepartment of Radiology, Nanhua Hospital Affiliated to Nanhua University, Hengyang, China.
Lijuan LaiDepartment of Radiology, Nanhua Hospital Affiliated to Nanhua University, Hengyang, China.
Derek CoricaDepartment of Microbiology, Immunology & Pathology, Des Moines University, Des Moines, United States of America.
Lijun DongDepartment of Obstetrics and Gynecology, the First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, China.
Yujiang FangDepartment of Microbiology, Immunology & Pathology, Des Moines University, Des Moines, United States of America.
Guojun SongDepartment of Radiology, Nanhua Hospital Affiliated to Nanhua University, Hengyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis review aims to evaluate the accuracy of Magnetic Resonance Imaging (MRI) in diagnosing Non-Alcoholic Fatty Liver Disease (NAFLD) based on the published literature.

methodsA PubMed search was performed using the keywords NAFLD and MRI, and the literature search deadline was set before April 2025.

resultsA total of 86 studies out of 405 retrieved were included in this study. The results showed that Magnetic Resonance Imaging Proton Density Fat Fraction (MRI-PDFF) was positively correlated with steatosis grading. The proton Density Fat Fraction Magnetic Resonance Spectroscopy (PDFFMRS) threshold of 5% could be used to diagnose liver steatosis. Apparent Diffusion Coefficient (ADC) of NAFLD patients was significantly lower than that of controls. A 15% increase in Magnetic Resonance Elastography (MRE) was the strongest predictor of progression to advanced fibrosis in NAFLD. The corrected T1 (cT1) cutoff value of 875 ms was used to identify liver fibrosis in NAFLD. The correlation between the Liver Surface Nodules (LSN) score and the stage of fibrosis in NAFLD was very strong. Dynamic enhanced MRI (DCE-MRI) parameters increased with increasing severity of NAFLD and fibrosis. DISCUSSION: This study evaluated the value of multiple MRI techniques in diagnosing NAFLD, confirming MRI's high accuracy and reliability as a noninvasive tool for quantifying NAFLD. However, future technical specification harmonization is needed to enhance comparability of results and validate generalizability through multicenter studies.

conclusionMRI is a highly reliable and accurate method for diagnosing NAFLD.

Indexed as

Magnetic Resonance ImagingNon-alcoholic Fatty Liver DiseaseElasticity Imaging TechniquesHumansDiagnosisMRINonalcoholic fatty liver disease.

Identifiers

PMID41572747
PMCPMC13639920

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.