Evidence map›Paper›PMID 41572604›Full record

ArticleClinical linguistics & phonetics

Vowel space change as a predictor of speech intelligibility gain in Down syndrome.

Delin Deng, Stephen Camarata, Julie Mazzone, Miriam Lense, Duane Watson

Abstract read
In one paragraph

Article in Clinical linguistics & phonetics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Delin DengDepartment of Psychology and Human Development, Vanderbilt University, Nashville, Tennessee, USA.ORCID 0000-0001-5389-1706
Stephen CamarataDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID 0000-0002-3342-1747
Julie MazzoneDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Miriam LenseDepartment of Otolaryngology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID 0000-0003-4362-3032
Duane WatsonDepartment of Psychology and Human Development, Vanderbilt University, Nashville, Tennessee, USA.

Funding

Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Jeffrey L Neul · 2020 to 2026
$10.3M
Predictors of Speech Ability in Children with Down SyndromeR21DC019280 · NIDCD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CAMARATA, STEPHEN MARK, LENSE, MIRIAM · 2021 to 2022
$635k
NICHD NIH HHS P50 HD103537NIDCD NIH HHS R21 DC019280
6 · The paper itself

Abstract

Reduced intelligibility is a frequent characteristic of the speech of children with Down syndrome (DS). While it is documented that compressed vowel space is often associated with low intelligibility, few studies have examined how acoustic vowel space changes during speech enrichment interventions are related to functional intelligibility gains. This study investigated whether change in acoustic vowel space can predict intelligibility improvement in DS. Thirteen children with DS completed a naturalistic speech enrichment intervention and were included in the present analysis. Vowel productions from a structured /hVt/ word task were acoustically analysed at baseline and post-speech enrichment interventions. To measure vowel space change, three metrics were used: articulatory-acoustic vowel space (AAVS), quadrilateral vowel space area (qVSA), and convex hull vowel space area (VSAhull). Intelligibility gains were measured using Growth Scale Values (GSVs) from the Woodcock Camarata Articulation Battery (WCAB). Regression analysis results revealed that changes in AAVS and VSAhull significantly predicted WCAB gains, while qVSA did not. These findings suggest that vowel space change reflects clinically meaningful articulatory adjustments, as indicated by their predictive association with intelligibility improvement following speech enrichment interventions. The lack of predictive power for qVSA highlights limitations of traditional corner-vowel metrics and supports the use of more comprehensive vowel space measures. While preliminary, these findings suggest that vowel space metrics may have future potential for clinical monitoring of speech development in children with DS, pending further validation in larger and more controlled studies.

Indexed as

Down SyndromePhoneticsSpeech AcousticsSpeech IntelligibilitySpeech TherapyChildChild, PreschoolFemaleHumansMaleSpeech Production MeasurementchildrenDown syndromeintelligibilityVowel space

Identifiers

PMID41572604
PMCPMC12959749

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.