Evidence map›Paper›PMID 41572578›Full record

ArticleACS applied bio materials2026

Precision Channel Engineering of Nanotube-Embedded Organic Electrochemical Transistors for Ultrasensitive Neurofilament Light Chain Detection.

Jia-Wei She, Lu-An Lin, Jayakrishnan Aerathupalathu Janardhanan, I-Chen Wang, Feng-Chen Hsu, Hsueh-Sheng Tseng, Yu-Sheng Hsiao, Hsiao-Hua Yu

Abstract read
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In one paragraph

Article in ACS applied bio materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jia-Wei SheSmart Organic Materials Laboratory, Institute of Chemistry, Academia Sinica, No. 128, Section 2, Academia Road, Nankang, Taipei 11529, Taiwan.
Lu-An LinCollege of Medicine, Chang Gung University, No. 259, Wenhua First Rd., Guishan Dist., Taoyuan City 33302, Taiwan.
Jayakrishnan Aerathupalathu JanardhananSmart Organic Materials Laboratory, Institute of Chemistry, Academia Sinica, No. 128, Section 2, Academia Road, Nankang, Taipei 11529, Taiwan.ORCID 0000-0002-8282-1333
I-Chen WangSmart Organic Materials Laboratory, Institute of Chemistry, Academia Sinica, No. 128, Section 2, Academia Road, Nankang, Taipei 11529, Taiwan.
Feng-Chen HsuDepartment of Materials Science and Engineering, National Taiwan University of Science and Technology, No. 43, Sec. 4, Keelung Rd., Taipei 106335, Taiwan.
Hsueh-Sheng TsengDepartment of Materials Science and Engineering, National Taiwan University of Science and Technology, No. 43, Sec. 4, Keelung Rd., Taipei 106335, Taiwan.
Yu-Sheng HsiaoDepartment of Materials Science and Engineering, National Taiwan University of Science and Technology, No. 43, Sec. 4, Keelung Rd., Taipei 106335, Taiwan.ORCID 0000-0003-2072-1844
Hsiao-Hua YuSmart Organic Materials Laboratory, Institute of Chemistry, Academia Sinica, No. 128, Section 2, Academia Road, Nankang, Taipei 11529, Taiwan.ORCID 0000-0002-3603-6932

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The quantitative monitoring of neurofilament light chain (Nf-L) is critical for the early diagnosis and prognosis of neurodegenerative disorders, such as amyotrophic lateral sclerosis (ALS), yet achieving femtomolar sensitivity in a portable, label-free format remains a formidable challenge. Here, we report a high-performance organic electrochemical transistor (OECT) immunosensor engineered via the precise template-free electropolymerization of a dual-functional poly(EDOT-COOH-

Indexed as

Biocompatible MaterialsBiosensing TechniquesElectrochemical TechniquesNanotubesNeurofilament ProteinsTransistors, ElectronicHumansMaterials TestingParticle SizeBiocompatible Materialsneurofilament protein LNeurofilament Proteinsbioelectronicsbiosensorsnanostructureneurofilament light chainorganic electrochemical transistorpoly(3,4-ethylenedioxythiophene)

Identifiers

PMID41572578
PMCPMC12914629

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.