Evidence map›Paper›PMID 41572414›Full record

ArticleJournal of paediatrics and child health2026

Management and Outcomes of Paediatric Bone and Joint Infections in a Regional Australian Hospital: A 10-Year Retrospective Study.

Niall Johnston, Rani Bhatia, Coen Butters

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Article in Journal of paediatrics and child health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Niall JohnstonDepartment of General Paediatric and Adolescent Medicine, John Hunter Children's Hospital, New Lambton Heights, New South Wales, Australia.ORCID https://orcid.org/0000-0002-2146-3253
Rani BhatiaDepartment of Paediatric Allergy and Immunology, John Hunter Children's Hospital, New Lambton Heights, New South Wales, Australia.
Coen ButtersDepartment of General Paediatric and Adolescent Medicine, John Hunter Children's Hospital, New Lambton Heights, New South Wales, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate clinical features, management, and outcomes of paediatric bone and joint infection (BJI) in a regional Australian hospital and assess weight-based oral antibiotic prescribing.

methodsWe conducted a retrospective study of 171 children aged 0-18 years admitted with septic arthritis and/or osteomyelitis between 2011 and 2021. Cases were identified using ICD-10-AM codes, and data on clinical presentation, microbiology and treatment were extracted from medical records. Oral antibiotic doses were assessed against international evidence-based guidelines.

resultsA total of 171 children were included (median age 27 months); 59.6% were aged ≤ 5 years, and 13.5% identified as Aboriginal or Torres Strait Islander. Staphylococcus aureus was the most frequently identified pathogen overall (53/108, 49.1%), and Kingella kingae in children < 5 years of age (20/57, 35.1%). Severe disease occurred in 29.8%. Oral antibiotic doses were below international guideline recommendations in 43.3% of cases, mostly with amoxicillin-clavulanate and cephalexin. Relapse (4.1%) and long-term sequelae (6.1%) were infrequent.

conclusionsPaediatric BJI mostly occurred in young and in Aboriginal and Torres Strait Islander children. Oral antibiotic weight-based dosing was often lower than international guideline recommendations for BJI. These findings highlight the need for standardised antibiotic dosing in BJI and further studies to optimise dosing in children.

Indexed as

Anti-Bacterial AgentsArthritis, InfectiousOsteomyelitisAdolescentAustraliaChildChild, PreschoolFemaleHumansInfantInfant, NewbornMaleRetrospective StudiesStaphylococcal InfectionsTreatment OutcomeAnti-Bacterial Agents

Identifiers

PMID41572414
PMCPMC12976197

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