Evidence map›Paper›PMID 41572407›Full record

ReviewAdvances in rheumatology (London, England)2026

Review of fibromyalgia treatment guidelines: part 2 - pharmacological treatment.

Roberto Ezequiel Heymann, Marcelo Cruz Rezende, Eduardo Dos Santos Paiva, Marcos Renato de Assis, Alessandra de Sousa Braz, Aline Ranzolin, Ana Paula Monteiro Gomides Reis, Andrea Pimentel Fonseca Golmia, Anna Beatriz Assad Maia, Denison Santos Silva and 14 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Advances in rheumatology (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Roberto Ezequiel HeymannHospital Israelita Albert Einstein, Sâo Paulo, Brazil. roberto.heymann@gmail.com.ORCID https://orcid.org/0000-0001-9552-7486
Marcelo Cruz RezendePain specialist certified by The Brazilian Medical Association, Sâo Paulo, Brazil.
Eduardo Dos Santos PaivaUniversidade Federal do Paranâ, Curitiba, Brazil.
Marcos Renato de AssisFaculdade de Medicina de Assis, Sâo Paulo, Brazil.
Alessandra de Sousa BrazHospital Universitârio Lauro Wanderley, Universidade Federal da Paraíba, Joâo Pessoa, Brazil.
Aline RanzolinHospital das Clínicas de Pernambuco, Recife PE, Brazil.
Ana Paula Monteiro Gomides ReisCentro Universitário de Brasília, Brasília, Brazil.
Andrea Pimentel Fonseca GolmiaHospital Israelita Albert Einstein, São Paulo, Brazil.
Anna Beatriz Assad MaiaUniversity Hospital of Brasília, Brasília, Brazil.
Denison Santos SilvaUniversidade Tiradentes, Aracaju, Sergipe, Brazil.
Fernando Augusto ChiuchettaHospital da XV, Curitiba, Brazil.
Gabriela GalassiBiomedical Researcher Axia Bio, Sâo Paulo, Brazil.
Izabela GuimarãesPain specialist certified by the Brazilian Medical Association (AMB), Sâo Paulo, Brazil.
José Eduardo MartinezPontifícia Universidade Católica de São Paulo, Sâo Paulo, Brazil.
José Roberto ProvenzaPontifícia Universidade Católica de Campinas, Sâo Paulo, Brazil.
Juliana Maria de Freitas Trindade CostaHospital de Aeronâutica de Recife, Recife, Brazil.
Marcos Paulo Veloso CorreiaUniversidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Marco Antônio Gonçalves Pontes FilhoPain specialist certified by the Brazilian Medical Association (AMB), Sâo Paulo, Brazil.
Marco Aurelio GoldenfumPontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.
Marcos Aurelio de Freitas MachadoMember of the International Association for the Study of Pain (IASP), Sâo Paulo, Brazil.
Melissa Mariti FragaUniversidade Federal de Sâo Paulo, Sâo Paulo, Brazil.
Nilton Salles Rosa NetoUniversidade Santo Amaro, Sâo Paulo, Brazil.
Rafael Navarrete FernandezPontificia Universidade Católica de Goiâs, Goiânia, Brazil.
Member of the Pain Committee of the Brazilian Society of Rheumatology

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fibromyalgia is a complex condition characterized by widespread chronic pain, fatigue, and sleep disturbances, which significantly affect quality of life. Its pathophysiology involves central sensitization (CS) and changes in neurotransmitters. Management is challenging and requires a multidisciplinary approach that integrates pharmacological and nonpharmacological treatments. This consensus, which is based on the BASCE system, presents updated guidelines for drug and nondrug treatments. The methodology focused on the evaluation of meta-analyses and systematic reviews of the literature and on voting by experts from the Brazilian Society of Rheumatology, ensuring recommendations with at least 70% agreement. Divided into two articles, this article addresses pharmacological strategies, incorporating recent advances to optimize clinical management and promote uniformity in professional practice.

Indexed as

FibromyalgiaPractice Guidelines as TopicAnalgesicsAntidepressive AgentsAntidepressive Agents, TricyclicDuloxetine HydrochlorideGabapentinHumansPregabalinSerotonin and Noradrenaline Reuptake InhibitorsAnalgesicsAntidepressive AgentsAntidepressive Agents, TricyclicDuloxetine HydrochlorideGabapentinPregabalinSerotonin and Noradrenaline Reuptake InhibitorsCentral sensitizationChronic painDuloxetineFibromyalgiaGabapentinGuidelinesPharmacological treatmentPregabalinSerotonin-norepinephrine reuptake inhibitors (SNRI)Tricyclic antidepressants (TCA)

Identifiers

PMID41572407
PMCPMC13472111

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.