Evidence map›Paper›PMID 41572383›Full record

ArticleBMC research notes2026

Clinical outcomes and feasibility of 3D-printed titanium alloy scaffolds combined with platelet-rich plasma injection in the treatment of long-segment femoral defects.

Rongda Xu, Jiahui Li, Hongliang Tu, Ming Sun, Zelin Zhang, Siyu Duan, Jiahe Wang, Zhencun Cai

Abstract read
In one paragraph

Article in BMC research notes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rongda Xu *Department of Orthopedic Surgery, The Second Affiliated Hospital of Shenyang Medical College, Shenyang, Liaoning, China.
Jiahui Li *Department of Orthopedic Surgery, The Second Affiliated Hospital of Shenyang Medical College, Shenyang, Liaoning, China.
Hongliang Tu *Department of Orthopedic Surgery, The Second Affiliated Hospital of Shenyang Medical College, Shenyang, Liaoning, China.
Ming SunDepartment of Orthopedic Surgery, The Second Affiliated Hospital of Shenyang Medical College, Shenyang, Liaoning, China.
Zelin ZhangDepartment of Orthopedic Surgery, The Second Affiliated Hospital of Shenyang Medical College, Shenyang, Liaoning, China.
Siyu DuanDepartment of Orthopedic Surgery, The Second Affiliated Hospital of Shenyang Medical College, Shenyang, Liaoning, China.
Jiahe WangDepartment of Family Medicine, Sheng Jing Hospital of China Medical University, Shenyang, Liaoning, China.
Zhencun CaiDepartment of Orthopedic Surgery, The Second Affiliated Hospital of Shenyang Medical College, Shenyang, Liaoning, China. sychczc@163.com.

Funding

Liaoning Provincial Department of Education Fund JYTMS20231396Science and Technology Fund of the Education Department of Liaoning Province 2024-MS-222
6 · The paper itself

Abstract

objectiveThis study aimed to investigate the clinical efficacy and feasibility of 3D-printed titanium alloy scaffolds combined with autologous platelet-rich plasma (PRP) injection in the treatment of long-segment femoral defects.

resultsThe mean follow-up duration for all patients in this study was 12.63 ± 1.02 months. At the final follow-up, the Visual Analogue Scale (VAS) score was 2.13 ± 1.15, significantly lower than the preoperative score of 6.31 ± 1.74 (P < 0.001). The Lower Extremity Functional Scale (LEFS) score was 54.88 ± 6.01, significantly higher than the preoperative score of 33.81 ± 8.05 (P < 0.001). The Lane–Sandhu score was 7.19 ± 1.38, and the patient-reported satisfaction score was 8.88 ± 1.02. No severe complications were observed during the follow-up period.

Indexed as

AlloysFemurPlatelet-Rich PlasmaPrinting, Three-DimensionalTissue ScaffoldsTitaniumAdultFeasibility StudiesFemaleHumansMaleTreatment OutcomeAlloysTitanium3D printingLong-segment bone defectsPlatelet-rich plasmaTitanium alloy scaffolds

Identifiers

PMID41572383
PMCPMC12911096

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.