Evidence map›Paper›PMID 41572351›Full record

ArticleTrials2026

Effects of varying inhaled oxygen concentrations on lung function in older adult patients undergoing laparoscopic gastrointestinal surgery under general anesthesia: protocol of a prospective multicenter clinical study in China.

Tianhao Zhang, Yang An, Shiling Zhao, Fei Han, Lining Huang, Li Wang, Jianbo Wu, Qian Lei, Kun Wang, Jianlin Shao and 10 more

Registry-linked trialAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06359106 (Effects of Different Inhaled Oxygen Concentrations on Lung Function in Older Patients After Laparoscopic Gastrointestinal Surgery Under General Anesthesia), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06359106 phase4recruitingnot on this map

Effects of Different Inhaled Oxygen Concentrations on Lung Function in Older Patients After Laparoscopic Gastrointestinal Surgery Under General Anesthesia

TypeinterventionalSponsorChina Medical University, ChinaRan2024 to 2026Enrolled1,176ConditionsOxygenation IndexArms80% Oxygen, 40% Oxygen
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Tianhao ZhangDepartment of Anesthesiology, The First Hospital of China Medical University, Shenyang, China.
Yang AnDepartment of Anesthesiology, The First Hospital of China Medical University, Shenyang, China.
Shiling ZhaoDepartment of Anesthesiology, Dalian Third People's Hospital, Dalian, China.
Fei HanDepartment of Anesthesiology, Harbin Medical University Cancer Hospital, Harbin, China.
Lining HuangDepartment of Anesthesiology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Li WangDepartment of Anesthesiology, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Jianbo WuDepartment of Anesthesiology, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, Jinan, China.
Qian LeiDepartment of Anesthesiology, Sichuan Provincial People's Hospital, Chengdu, China.
Kun WangDepartment of Anesthesiology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Jianlin ShaoDepartment of Anesthesiology, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Yun WangDepartment of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Yong LuanDepartment of Anesthesiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Wei FengDepartment of Anesthesiology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Jiannan SongDepartment of Anesthesiology, Chifeng Municipal Hospital, Chifeng, China.
Zeqing HuangDepartment of Anesthesiology, Liaoning Cancer Hospital & Institute, Shenyang, China.
Chaoran WuDepartment of Anesthesiology, Shenzhen People's Hospital, Shenzhen, China.
Yongshan NanDepartment of Anesthesiology, Yanbian University Hospital (Yanbian Hospital), Yanji, China.
Bing TangDepartment of Anesthesiology, The First Hospital of China Medical University, Shenyang, China.
Xijia SunDepartment of Anesthesiology, The First Hospital of China Medical University, Shenyang, China.
Wenfei TanDepartment of Anesthesiology, The First Hospital of China Medical University, Shenyang, China. wftan@cmu.edu.cn.

Funding

Innovative Research Group Project of the National Natural Science Foundation of China Grant No. 82171187Wu Jieping Medical Foundation Project NO.320.6750.2024-05-14
6 · The paper itself

Abstract

backgroundPostoperative pulmonary complications (PPCs) are severe and are of particular concern in older adult patients undergoing laparoscopic gastrointestinal surgery. Both 40% and 80% fraction of inspired oxygen (FiO

methodsThis multicenter, prospective, parallel-cohort, randomized controlled clinical trial will include 1098 older adult participants aged ≥ 65 years old undergoing laparoscopic gastrointestinal surgery, from 16 clinical trial sites across China. Participants will be randomized, as per a 1:1 ratio to two cohorts, the "L" and "H" cohorts, to receive low FiO DISCUSSION: This study of elderly patients undergoing laparoscopic gastrointestinal surgery with different intraoperative oxygen concentrations at high risk for pulmonary complications. All subjects were followed up for up to 30 days for pulmonary function, postoperative complications, etc. Randomization was performed separately at 16 sites.

trial registrationClinicalTrials.gov NCT06359106. Registered and posted on April 11, 2024.

Indexed as

Anesthesia, GeneralDigestive System Surgical ProceduresLaparoscopyLungLung DiseasesOxygenOxygen Inhalation TherapyPostoperative ComplicationsAgedAge FactorsChinaFemaleGeriatric AnesthesiaHumansMaleMulticenter Studies as TopicOxygenAbsorption atelectasisFraction of inspired oxygenLaparoscopic gastrointestinal surgeryOlder adult patientsPostoperative pulmonary complications

Identifiers

PMID41572351
PMCPMC12910851

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.