Evidence map›Paper›PMID 41572237›Full record

Observational studyBMC women's health2026

Returning to work after breast cancer diagnosis: a cross-sectional study of socioeconomic and clinical factors associated with return to work in Luxembourg.

Allini Mafra, Mounir Talbi, Geraldine Cassells, Sandrine Lavalle, Marc Suhrcke, Martine Georges, Nicole Majery, Claudine Backes

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC women's health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Allini MafraRegistre National du Cancer du Luxembourg (RNC), Strassen, Luxembourg. Allini.MafraDaCosta@lih.lu.
Mounir TalbiRegistre National du Cancer du Luxembourg (RNC), Strassen, Luxembourg.
Geraldine CassellsDepartment of Communication and Marketing, Patient & Public Involvement, Luxembourg Institute of Health, Strassen, Luxembourg.
Sandrine LavalleDepartment of Communication and Marketing, Patient & Public Involvement, Luxembourg Institute of Health, Strassen, Luxembourg.
Marc SuhrckeLuxembourg Institute of Socio-Economic Research (LISER), Luxembourg, Luxembourg.
Martine GeorgesService de santé au travail multisectoriel, Luxembourg, Luxembourg.
Nicole MajeryService de santé au travail multisectoriel, Luxembourg, Luxembourg.
Claudine BackesRegistre National du Cancer du Luxembourg (RNC), Strassen, Luxembourg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBreast cancer (BC) is one of the most common cancers affecting women globally, with consequences for health, quality of life, and socioeconomic status. Return-to-work (RTW) represents an important milestone for women affected by BC. This study analyses clinical, sociodemographic and socioeconomic factors associated with RTW among women in Luxembourg after BC diagnosis, aiming to identify factors associated with RTW outcomes.

methodsThis study, conducted under the RELIANCE project, involved an observational, cross-sectional, questionnaire-based pilot study addressing RTW among women diagnosed with BC. Eligible participants were women diagnosed with BC between 2013 and 2018, aged < 65 years at diagnosis, employed in Luxembourg at that time and who had undergone an examination at Service de santé au travail multisectoriel. Of 452 invited women, 164 (39% response rate) completed the questionnaire. Descriptive and multivariable analyses were conducted to assess associations between clinical, socio-demographic and socioeconomic characteristics and RTW outcomes.

resultsOverall, 83% of participants returned to work after BC. Advanced higher education was independently associated with higher odds of RTW (OR = 44.0; 95% CI: 1.52–1272.0; p = 0.028), while higher education showed a borderline association (OR = 6.07; 95% CI: 0.96–38.4; p = 0.055). Experiencing premature menopause was also associated with increased odds of RTW (OR = 8.54; 95% CI: 1.58–46.1; p = 0.013). Absence of comorbidities before BC was associated with higher RTW (p = 0.032). Job satisfaction improved after BC (median 7 to 8), while perceived work ability declined (median 9 to 7). In the multivariable linear model, work ability before BC was significantly associated with higher job satisfaction after BC (coefficient = 0.28; 95% CI: 0.02–0.54; p = 0.036), and job satisfaction before BC showed a positive but non-significant association.

conclusionSocioeconomic factors, particularly educational attainment, and clinical factors such as premature menopause were independently associated with RTW outcomes among women affected by BC in Luxembourg. Job satisfaction after BC was influenced by women’s work ability before BC, with workplace social support contributing to a lesser extent. Targeted interventions addressing educational disparities, along with workplace support initiatives, are essential to improving RTW outcomes in this population. Longitudinal studies are needed to explore these associations further and identify potential intervention points.

Indexed as

Breast NeoplasmsReturn to WorkAdultCross-Sectional StudiesEducational StatusFemaleHumansLuxembourgMiddle AgedPilot ProjectsQuality of LifeSocioeconomic FactorsSurveys and QuestionnairesBreast cancerReturn to workSociodemographic factorsSocioeconomic factors

Identifiers

PMID41572237
PMCPMC12911227

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.