Evidence map›Paper›PMID 41572087›Full record

ArticleThe Saudi dental journal2026

Do irrigating solutions influence the cyclic fatigue resistance of heat-treated NiTi instruments? an in vitro study.

Christoph Matthias Schoppmeier, Malin Janson, Li Sun, Gustav Leo Classen, Anna Greta Barbe

Abstract read
In one paragraph

Article in The Saudi dental journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christoph Matthias SchoppmeierPolyclinic for Operative Dentistry and Periodontology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Kerpener Str. 32, 50931, Cologne, Germany. christoph.schoppmeier@uk-koeln.de.ORCID http://orcid.org/0000-0002-3269-8920
Malin JansonDepartment of Prosthetic Dentistry, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.ORCID http://orcid.org/0009-0006-6486-6825
Li SunPolyclinic for Operative Dentistry and Periodontology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Kerpener Str. 32, 50931, Cologne, Germany.ORCID http://orcid.org/0009-0002-7251-7976
Gustav Leo ClassenPolyclinic for Operative Dentistry and Periodontology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Kerpener Str. 32, 50931, Cologne, Germany. gustav.classen1@uk-koeln.de.ORCID http://orcid.org/0000-0003-4903-6605
Anna Greta BarbePolyclinic for Operative Dentistry and Periodontology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Kerpener Str. 32, 50931, Cologne, Germany. greta.barbe@uk-koeln.de.ORCID http://orcid.org/0000-0003-0169-2582

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeNickel-titanium (NiTi) instruments have advanced root canal preparation through enhanced precision. Thermal pretreatment improves both flexibility and cyclic fatigue resistance (CFR). While irrigating solutions are essential for decontamination, they may also affect the properties of heat-treated NiTi instruments. This study aimed to evaluate the impact of different irrigating solutions on the cyclic fatigue resistance of heat-treated NiTi files.

methodsFour heat-treated reciprocating NiTi-files were analyzed: EdgeOne R-Utopia, Reciproc Blue, Procodile Q and CC One Blue. Files were immersed (5 min; 37 °C and 60 °C) in 5.25% sodium hypochlorite (NaOCl), 17% ethylenediaminetetraacetic acid (EDTA), 96% ethanol, NaOCl + EDTA, distilled water, or left in a no-immersion control group. CFR was measured in an artificial root canal (60° curvature, 5 mm radius), and fragment length (FL) was documented. The surface features of the fragments were assessed through scanning electron microscopy.

resultsFile system, irrigating solution, and temperature significantly influenced CFR (p < 0.001). Across all immersion conditions, the CFR reached its highest value with Procodile Q (37 °C distilled water) and its lowest with EdgeOne R-Utopia (60 °C NaOCl + EDTA). EDTA reduced CFR across all files, particularly at elevated temperatures and when combined with NaOCl. Microscopy revealed micropitting and roughened surfaces, particularly on CC One Blue (60 °C NaOCl), as well as material degradation and heterogeneous surfaces with NaOCl + EDTA.

conclusionsHeat-treated NiTi instruments are influenced in their mechanical and metallurgical behavior by the chemical and thermal impact of irrigating solutions. Heated EDTA and NaOCl + EDTA were detrimental, while Procodile Q demonstrated the highest CFR. Within the limitations of this study, exposure to irrigating solutions, particularly heated EDTA and NaOCl + EDTA, reduced the cyclic fatigue resistance of heat-treated NiTi files. Clinically, prudent selection and temperature control of irrigants may help preserve instrument performance and reduce the risk of file fracture during root canal preparation.

Indexed as

Cyclic fatigue resistanceEndodontic irrigantsEthylenediaminetetraacetic acid (EDTA)Nickel-Titanium instrumentsSodium hypochloriteSurface corrosion

Identifiers

PMID41572087
PMCPMC12827828

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.