Evidence map›Paper›PMID 41572059›Full record

ArticleLasers in medical science2026

Role of photobiomodulation in controlling the gag reflex during posterior tooth extraction, a pilot case series.

Zeynep Çukurova Yılmaz, İpek Necla Güldiken, Alperen Tekin, Hayrunisa Koçyiğit Daştan, Buğra Düç

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Article in Lasers in medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Zeynep Çukurova YılmazIstanbul Medipol University, Istanbul, Turkey.
İpek Necla Güldikenİstinye University, Istanbul, Turkey.
Alperen TekinIstanbul Medeniyet University, Istanbul, Turkey. alperen.tekin@medeniyet.edu.tr.
Hayrunisa Koçyiğit DaştanIstanbul Medipol University, Istanbul, Turkey.
Buğra DüçIstanbul Medipol University, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This pilot case series aimed to investigate the feasibility and preliminary efficacy of photobiomodulation (PBM; also known as low-level laser therapy [LLLT]) applied to specific acupuncture points (PC6 and CV24) in managing the gag reflex during posterior single-tooth extraction. Participants with moderate-to-severe gag reflex (n = 20) were selected based on Gagging Severity Index (GSI) scores ≥ 3 during clinical examination. Gag reflex severity was measured using both the GSI and the Predictive Gagging Survey (PGS) before and after the procedure. LLLT (976 nm diode laser, 100 mW, 4 J/cm² per point, continuous-wave, 20 s per point, 8-mm diameter tip [spot area ≈ 0.50 cm²]) was administered immediately prior to extraction. Preoperative GSI scores (3.3 ± 0.6) underwent a significant decrease postoperatively (1.3 ± 0.5; P < 0.001). Concurrently, PGS scores showed a moderate positive correlation with baseline GSI. LLLT was found to be an effective method of controlling the gag reflex during posterior tooth extraction, thereby facilitating the procedure. In this pilot study, LLLT was associated with reduced gag reflex during posterior tooth extraction. However, the absence of a control group should be acknowledged as a limitation, and the findings should be interpreted with caution. Controlled trials are needed to confirm these preliminary results.

Indexed as

GaggingLow-Level Light TherapyTooth ExtractionAcupuncture PointsAdultFemaleHumansLasers, SemiconductorMaleMiddle AgedPilot ProjectsAcupuncture pointsGaggingLow-Level light therapyTooth extraction

Identifiers

PMID41572059
PMCPMC12827443

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.