Evidence map›Paper›PMID 41571900›Full record

SynthesisNaunyn-Schmiedeberg's archives of pharmacology2026

Emerging trends and hotspots in Oseltamivir resistance: insights from a bibliometric investigation.

Siming Zhai, Yuzhu Dou, Zhengjiu Cui, Bin Yuan

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Naunyn-Schmiedeberg's archives of pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Siming ZhaiAffiliated Hospital of Nanjing University of Chinese Medicine, Nanjing University of Chinese Medicine, Nanjing, China.
Yuzhu DouAffiliated Hospital of Nanjing University of Chinese Medicine, Nanjing University of Chinese Medicine, Nanjing, China.
Zhengjiu CuiAffiliated Hospital of Nanjing University of Chinese Medicine, Nanjing University of Chinese Medicine, Nanjing, China.
Bin YuanAffiliated Hospital of Nanjing University of Chinese Medicine, Nanjing University of Chinese Medicine, Nanjing, China. yfy0045@njucm.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Influenza has long been a serious global public health problem, and the risk of drug resistance to Oseltamivir, as a first-line antiviral drug, cannot be ignored. Although some research findings have been published, a systematic review of current research on Oseltamivir resistance is lacking. Therefore, we employed a bibliometric method to conduct comprehensive search and to present current trends. Based on the screening criteria, literature related to Oseltamivir resistance from 2000 To 2024 was retrieved from the Web of Science Core Collection (WOSCC). Citespace and Bibliometrix were used to analyze and visualize the indicators (country, institution, journal, author, keywords, references) of the included literature. This study compiled 5159 articles from 1996 To 2024. The number of publications has shown a fluctuating upward trend, with the most research published in 2011, followed by a slight decline and then another increase. The United States and China have the highest number of publications, and the Centers for Disease Control and Prevention (CDC) has the highest number of institutions publishing. Hurt, AC, and Hayden, FG are the most influential authors and co-cited authors in this field. Antiviral Research and the New England Journal of Medicine are the journals with the highest output and citation frequency, respectively. The reference with the highest outbreak intensity is HAYDEN FG, 1999, NEW ENGL J MED, V341, P1336. Influenza virus subtypes, including H1N1 and H5N1, neuraminidase inhibitors, and drug safety are currently hot and cutting-edge research topics in this field. Based on the comprehensive literature analysis, this study summarizes the current status of Oseltamivir resistance and identifies emerging trends. These discoveries provide a reference for exploring the mechanisms, epidemiological patterns, clinical impacts, and response strategies of Oseltamivir resistance. Future research could strengthen international collaboration and cooperation to reveal and propose innovative solutions or recommendations from multiple perspectives, contributing to the development of global public health.

Indexed as

Antiviral AgentsDrug Resistance, ViralInfluenza, HumanOseltamivirBibliometricsHumansNeuraminidaseAntiviral AgentsNeuraminidaseOseltamivirBibliometric analysisNeuraminidase inhibitorOseltamivir resistanceVisual analyticsWeb of science

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.