Evidence map›Paper›PMID 41571857›Full record

ArticleLangenbeck's archives of surgery2026

Perioperative selective decontamination of the digestive tract does not improve postoperative infectious complications after gastrectomy: a propensity score-matched analysis.

Jasmin Hasanovic, Floris Berg, Christian Teske, Marius Distler, Jürgen Weitz, Daniel E Stange, Felix Merboth

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Langenbeck's archives of surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Jasmin HasanovicDepartment of Visceral, Thoracic, and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307, Dresden, Germany. jasmin.hasanovic@ukdd.de.
Floris BergDepartment of Visceral, Thoracic, and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
Christian TeskeDepartment of Visceral, Thoracic, and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
Marius DistlerDepartment of Visceral, Thoracic, and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
Jürgen WeitzDepartment of Visceral, Thoracic, and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
Daniel E StangeDepartment of Visceral, Thoracic, and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
Felix MerbothDepartment of Visceral, Thoracic, and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeInfectious complications remain a significant cause of morbidity after gastrectomy for gastric cancer. Selective decontamination of the digestive tract (SDD) is effective in colorectal surgery, but its role in upper gastrointestinal procedures is unclear.

methodsWe conducted a retrospective cohort study of patients undergoing open gastrectomy between 2014 and 2024. Patients treated with perioperative SDD (2018–2024) were compared with a matched historical cohort without SDD (2014–2018) using 1:1 propensity score matching (PSM). The primary endpoint was infectious complications.

resultsA total of 108 patients were matched (54 SDD, 54 non-SDD). Rates of major complications (16.7% vs. 14.8%), anastomotic leakage (5.6% vs. 3.7%), superficial surgical site infections (SSIs) (14.8% vs. 11.1%), and organ/space infections (7.4% vs. 13.0%) were similar between the two groups. However, pneumonia occurred significantly more frequently in the SDD group (18.5% vs. 3.7%, p = 0.029). Microbiological analyses revealed more enterobacteriaceae and enterococci in the SDD group, with resistant isolates detected exclusively in this cohort.

conclusionSDD did not reduce infectious complications after gastrectomy and was associated with higher pneumonia rates and the emergence of resistant isolates. These findings question its routine use in gastric cancer surgery and highlight the need for further prospective evaluation.

Indexed as

DecontaminationGastrectomyPerioperative CarePostoperative ComplicationsStomach NeoplasmsSurgical Wound InfectionAgedAnti-Bacterial AgentsFemaleHumansMaleMiddle AgedPropensity ScoreRetrospective StudiesAnti-Bacterial AgentsAnastomotic leakGastrectomyGastric cancerPneumoniaPropensity score matchingSelective decontamination of the digestive tractSurgical site infection

Identifiers

PMID41571857
PMCPMC12855432

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.