Evidence map›Paper›PMID 41571830›Full record

ArticleScientific reports2026

Derivation of an intrinsic brain activity biomarker for the earliest prediction of cognitive decline.

Leslie S Prichep, Syed N Zaidi, Kara Brink, Saloni Kanakia, Bo Liang, Yang Jiang, Ruben Armañanzas

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Leslie S PrichepBrainScope Company, Rockville, MD, 20855, USA. leslie.prichep@brainscope.com.
Syed N ZaidiBrainScope Company, Rockville, MD, 20855, USA.
Kara BrinkBrainScope Company, Rockville, MD, 20855, USA.
Saloni KanakiaBrainScope Company, Rockville, MD, 20855, USA.
Bo LiangBrainScope Company, Rockville, MD, 20855, USA.
Yang JiangAging Brain and Cognition Laboratory, Department of Behavioral Science, College of Medicine, University of Kentucky, Lexington, KY, USA.
Ruben ArmañanzasInstitute of Data Science and Artificial Intelligence (DATAI), Universidad de Navarra, Pamplona, Spain.

Funding

PSYCHOSOCIAL COREP30AG008051 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SHAO, YONGZHAO · 1990 to 2019
$36.1M
ZOPOLRESTAT IN SUBJECTS W/ PERIPHERAL SYMMETRICAL DIABETIC POLYNEUROPATHYM01RR000096 · NCRR · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BORKOWSKY, WILLIAM · 1985 to 2008
$34.8M
University of Kentucky Alzheimer's Disease Research CenterP30AG072946 · NIA · UNIVERSITY OF KENTUCKY · PI LINDA J VAN ELDIK · 2021 to 2026
$23.5M
TRAINING AND INFORMATION TRANSFER COREP50AG005144 · NIA · UNIVERSITY OF KENTUCKY · PI MARKESBERY, WILLIAM R · 1985 to 2005
$8.9M
AGING AND DEMENTIA--LONGITUDINAL STUDYR01AG003051 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI REISBERG, BARRY · 1987 to 2002
$850k
Neuroimaging of Complex Motion in Young and Old AdultsK01AG000986 · NIA · UNIVERSITY OF KENTUCKY · PI JIANG, YANG · 2001 to 2005
$584k
Predictive Neurophysiological Biomarkers for Risk of Alzheimer’s Disease (AD) and Related Dementia (ADRD) Induced Cognitive Impairment in Sino-US CohortsR56AG060608 · NIA · UNIVERSITY OF KENTUCKY · PI JIANG, YANG · 2018 to 2018
$440k
Alzheimer's Drug Discovery Foundation # GC-202202-2022659NCRR NIH HHS M01 RR000096NIA NIH HHS K01 AG000986NIA NIH HHS P30 AG008051NIA NIH HHS P30 AG072946NIA NIH HHS P50 AG005144NIA NIH HHS R01 AG003051NIA NIH HHS R56 AG060608
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41571830
PMCPMC12886770

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.