Evidence map›Paper›PMID 41571432›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2026

Subtracting First Principal Component May Improve 4R Tau Detectability on [

Ryota Satoh, Farwa Ali, Dennis W Dickson, Val J Lowe, Keith A Josephs, Jennifer L Whitwell

Abstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ryota SatohDepartment of Radiology, Mayo Clinic, Rochester, Minnesota; satoh.ryota@mayo.edu.
Farwa AliDepartment of Neurology, Mayo Clinic, Rochester, Minnesota; and.
Dennis W DicksonDepartment of Neuroscience, Mayo Clinic, Jacksonville, Florida.
Val J LoweDepartment of Radiology, Mayo Clinic, Rochester, Minnesota.
Keith A JosephsDepartment of Neurology, Mayo Clinic, Rochester, Minnesota; and.
Jennifer L WhitwellDepartment of Radiology, Mayo Clinic, Rochester, Minnesota.

Funding

Longitudinal multi-modality imaging in progressive apraxia of speech (Diversity Supplement)R01DC012519 · NIDCD · MAYO CLINIC ROCHESTER · PI Jennifer Louise Whitwell · 2013 to 2026
$7.2M
Longitudinal Multi-modal Imaging in Progressive Supranuclear Palsy SyndromesR01NS089757 · NINDS · MAYO CLINIC ROCHESTER · PI JOSEPHS, KEITH A, WHITWELL, JENNIFER LOUISE · 2015 to 2024
$5.6M
Longitudinal multi-modal imaging in progressive supranuclear palsy syndromesR37NS089757 · NINDS · MAYO CLINIC ROCHESTER · PI Keith A Josephs, Jennifer Louise Whitwell · 2026 to 2026
$3.7M
Flortaucipir PET and histopathology in frontotemporal lobar degeneration and Alzheimer’s diseaseR01NS112153 · NINDS · MAYO CLINIC ROCHESTER · PI JOSEPHS, KEITH A, WHITWELL, JENNIFER LOUISE · 2024 to 2025
$767k
NIDCD NIH HHS R01 DC012519NINDS NIH HHS R01 NS089757NINDS NIH HHS R01 NS112153NINDS NIH HHS R37 NS089757
6 · The paper itself

Abstract

[

Indexed as

CarbolinesPositron-Emission TomographyPrincipal Component Analysistau ProteinsAgedFemaleHumansMaleMiddle AgedSensitivity and SpecificitySupranuclear Palsy, Progressive7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indoleCarbolinestau Proteins[18F]flortaucipir4R tauprincipal component analysisPSP

Identifiers

PMID41571432
PMCPMC13041585

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.