Evidence map›Paper›PMID 41571024›Full record

ArticleThe Annals of thoracic surgery2026

Durability and Outcomes of Mitral Reintervention After Surgical Mitral Repair in Patients 65 Years and Older in the United States.

Aminah Sallam, Sundos Alabbadi, Michael E Bowdish, Derrick Y Tam, Allen A Razavi, Betemariam Sharew, Shubhadarshini Pawar, Dominic Emerson, Natalia Egorova, Joanna Chikwe

Abstract read
In one paragraph

Article in The Annals of thoracic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aminah SallamDepartment of Cardiac Surgery, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California.
Sundos AlabbadiDepartment of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, New York.
Michael E BowdishDepartment of Cardiac Surgery, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California.
Derrick Y TamDepartment of Cardiac Surgery, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California; Division of Cardiac Surgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
Allen A RazaviDepartment of Cardiac Surgery, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California.
Betemariam SharewDepartment of Cardiac Surgery, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California.
Shubhadarshini PawarDepartment of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California.
Dominic EmersonDepartment of Cardiac Surgery, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California.
Natalia EgorovaDepartment of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, New York.
Joanna ChikweDepartment of Cardiac Surgery, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California. Electronic address: joanna.chikwe@cshs.org.

Funding

Training in Advanced Heart Disease ResearchT32HL116273 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI Joshua I Goldhaber, EDUARDO MARBAN · 2013 to 2026
$5.6M
NHLBI NIH HHS T32 HL116273
6 · The paper itself

Abstract

backgroundNational data on the durability of surgical mitral repair and outcomes of reintervention are lacking. This study aimed to quantify the national incidence and outcomes of mitral reintervention after surgical repair.

methodsThe US Centers for Medicare & Medicaid Services claims identified patients aged ≥65 years who underwent surgical mitral repair followed by reintervention (replacement, repeat repair, or transcatheter edge-to-edge repair [TEER]) between 2012 and 2023. The 30-day and 3-year mortality, stroke, and heart failure readmission after reintervention were assessed using logistic regression and adjusted Cox proportional hazards modeling. Competing risks were used to estimate the probability of reintervention, heart failure, and stroke.

resultsOf 45,482 patients undergoing surgical mitral repair, 1560 required reintervention. Of these, 1223 (78.4%) had surgical replacement, 164 (10.5%) underwent surgical repair, and 173 (11.1%) had TEER. The median time to reintervention was 1.9 years (interquartile range, 0.64-4.1 years). The cumulative incidence of reintervention at 9 years was 5%. The adjusted 30-day rate of heart failure readmission was lowest among patients who underwent TEER (4.8% vs 15.9% replacement, vs 14.6% repeat repair; P < .01), whereas 30-day mortality and stroke readmission rates did not differ among the reintervention approaches. At 3 years, there was no significant difference in survival, heart failure readmissions, or stroke readmissions by reintervention approach.

conclusionsSurgical mitral repair is durable, with a low 9-year risk of reintervention. The reintervention approach does not affect mortality, heart failure, and stroke readmissions at 3 years, a finding suggesting that any of these approaches is appropriate for reintervention.

Indexed as

Heart Valve Prosthesis ImplantationMitral ValveMitral Valve InsufficiencyPostoperative ComplicationsReoperationAgedAged, 80 and overFemaleHeart FailureHumansIncidenceMalePatient ReadmissionRetrospective StudiesStrokeTreatment Outcome

Identifiers

PMID41571024
PMCPMC13124310

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.