Evidence map›Paper›PMID 41570797›Full record

ArticleNeuron2026

From tumor metabolism to brain circuits: METTL14 as a SAM sensor driving pain-depression in pancreatic cancer.

Paola D Vermeer

Abstract read
In one paragraph

Article in Neuron, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Paola D VermeerSanford Research, 2301 East 60(th) Street North, Sioux Falls, SD 57104, USA; Department of Surgery, University of South Dakota, Sanford School of Medicine, 414 E. Clark Street, Vermillion, SD 57069, USA. Electronic address: paola.vermeer@sanfordhealth.org.

Funding

Pilot Project ProgramP30GM145398 · NIGMS · SANFORD RESEARCH/USD · PI W KEITH MISKIMINS · 2023 to 2026
$6.2M
Intra-tumoral neurons contribute to head and neck cancer painR01DE032712 · NIDCR · SANFORD RESEARCH/USD · PI Paola Drapkin Vermeer · 2023 to 2026
$1.8M
NIDCR NIH HHS R01 DE032712NIGMS NIH HHS P30 GM145398
6 · The paper itself

Abstract

Our knowledge gaps regarding the mechanisms driving the varied signs and symptoms associated with malignancies are quickly being filled. In this edition, Yang et al. discover a critical connection linking pancreatic cancer and its associated comorbidities-pain and depression.

Indexed as

BrainDepressionPainPancreatic NeoplasmsAnimalsHumans

Identifiers

PMID41570797
PMCPMC13220295

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.