Evidence map›Paper›PMID 41570075›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Metabolic rewiring and biomass redistribution enable optimized mixotrophic growth in Chlamydomonas.

Somnath Koley, Kevin Foley, Zoee Perrine, Stewart A Morley, Shrikaar Kambhampati, Olivia Gomez, Kevin L Chu, Yi-Hsiang Chou, Michael Wei, Shin-Cheng Tzeng and 3 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. A Low-DimensionalMolecules (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Somnath Koley *Donald Danforth Plant Science Center, St. Louis, MO 63132.
Kevin Foley *Donald Danforth Plant Science Center, St. Louis, MO 63132.
Zoee PerrineDonald Danforth Plant Science Center, St. Louis, MO 63132.
Stewart A MorleyDonald Danforth Plant Science Center, St. Louis, MO 63132.
Shrikaar KambhampatiDonald Danforth Plant Science Center, St. Louis, MO 63132.ORCID 0000-0003-1582-0733
Olivia GomezDonald Danforth Plant Science Center, St. Louis, MO 63132.ORCID 0000-0003-3110-6476
Kevin L ChuDonald Danforth Plant Science Center, St. Louis, MO 63132.
Yi-Hsiang ChouDonald Danforth Plant Science Center, St. Louis, MO 63132.
Michael WeiDonald Danforth Plant Science Center, St. Louis, MO 63132.ORCID 0000-0002-2224-6496
Shin-Cheng TzengDonald Danforth Plant Science Center, St. Louis, MO 63132.ORCID 0000-0002-1095-7418
Russell WilliamsDonald Danforth Plant Science Center, St. Louis, MO 63132.ORCID 0000-0003-4534-3173
James G UmenDonald Danforth Plant Science Center, St. Louis, MO 63132.ORCID 0000-0003-4094-9045
Doug K AllenDonald Danforth Plant Science Center, St. Louis, MO 63132.ORCID 0000-0001-8599-8946

Funding

NSF (NSF) DBI-1616820NSF (NSF) DBI-1829365NSF (NSF) DBI-2242822USDA | National Institute of Food and Agriculture (NIFA) 2017-67013-26156USDA | National Institute of Food and Agriculture (NIFA) 2021-67013-33778USDA | National Institute of Food and Agriculture (NIFA) 2023-67017-39419U.S. Department of Energy (DOE) DE-SC0022207U.S. Department of Energy (DOE) DE SC0023142
6 · The paper itself

Abstract

Aquatic photosynthetic systems account for approximately one-half of all global carbon assimilation and could be a significant source of renewable fuels and feedstocks. However, rapid growth and biomass production in algae have not always translated into high product yields, partly because central metabolism is context specific, with metabolic fluxes being influenced by nutrient conditions and other environmental factors. In the green microalga

Indexed as

BiomassChlamydomonasChlamydomonas reinhardtiiAcetatesCarbonCarbon IsotopesGluconeogenesisGlyoxylatesMetabolic Flux AnalysisPhotosynthesisAcetatesCarbonCarbon IsotopesGlyoxylatesalgaecentral carbon metabolismglyoxylate cycleisotopic labelingmetabolic flux analysis

Identifiers

PMID41570075
PMCPMC12846818

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.