ArticleNeonatology2026
Patterns of Neonatal and Neurodevelopmental Comorbidities in Neonates of <29 Weeks' Gestation.
Article in Neonatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Preterm Children in Iceland: Neonatal Morbidities and Motor Development in the First Two Years, and Later Disability Diagnosis.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
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7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
<p>Introduction: Multi-morbidity is a known cause of adverse outcomes and resource utilization in adults. Our objective was to describe the co-occurrence of neonatal morbidities and their association with neurodevelopmental outcomes in preterm neonates.
methodsWe included 17,438 preterm neonates of <29 weeks' gestation admitted to Canadian neonatal intensive care units between 2010 and 2020, of whom 7,943 children had neurodevelopmental information. Neonatal outcomes were mortality, late-onset sepsis, necrotizing enterocolitis, and severe neurological injury. The outcomes were neurodevelopmental impairments, with significant impairment defined as any of: Bayley Scales of Infant and Toddler Development-third edition (Bayley-III) score of <70, cerebral palsy with Gross Motor Function Classification System (GMFCS) of ≥3, hearing amplification, or bilateral visual impairment; and severe impairment defined as any of: Bayley-III score of <55, cerebral palsy with GMFCS of 4-5, or bilateral blindness.
resultsThe mean (standard deviation) gestational age was 26.1 (1.6) weeks and 54.5% were male. Any neonatal mortality/morbidity occurred in 40.1% of children. Among survivors, 16.3% had significant neurodevelopmental impairment and 5.8% had severe neurodevelopmental impairment. However, 51% of children with significant impairment and 43% with severe neurodevelopmental impairment had no neonatal morbidities. Late-onset sepsis (aOR 1.60, 95% CI: 1.36, 1.88), necrotizing enterocolitis (aOR 1.91, 95% CI: 1.36, 2.69), and severe neurological injury (aOR 3.54, 95% CI: 2.85, 4.38) were associated with significant neurodevelopmental impairment among survivors. An increase in the count of neonatal morbidities correlated with a rise in the count of neurodevelopmental impairments.
conclusionsSixty percent of infants of <29 weeks' gestation experienced no adverse neonatal outcomes and the majority were free of significant neurodevelopmental impairment. Neonatal morbidities had a direct and combined association with neurodevelopmental impairment. </p>.
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