Evidence map›Paper›PMID 41569524›Full record

ArticleJMIR research protocols2026

Investigating the Role of the Environment on Physical Activity Interventions (the InSPACE Project): Protocol for a Pooled Secondary Analysis of Randomized Controlled Trials.

Amy J Youngbloom, Maya Rowland, Stephen J Mooney, Kaitlin Singer, Adam Szpiro, Brian E Saelens

Abstract read
In one paragraph

Article in JMIR research protocols, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amy J YoungbloomDepartment of Epidemiology, School of Public Health, University of Washington, 3980 15th Ave NE, Seattle, WA, 98195, United States, 1 2065431065.ORCID 0000-0002-6095-0580
Maya RowlandCenter for Child Health, Behavior and Development, Seattle Children's Research Institute, Seattle, WA, United States.ORCID 0009-0002-8352-1444
Stephen J MooneyDepartment of Epidemiology, School of Public Health, University of Washington, 3980 15th Ave NE, Seattle, WA, 98195, United States, 1 2065431065.ORCID 0000-0001-9092-938X
Kaitlin SingerDepartment of Epidemiology, School of Public Health, University of Washington, 3980 15th Ave NE, Seattle, WA, 98195, United States, 1 2065431065.ORCID 0000-0002-7575-5446
Adam SzpiroDepartment of Biostatistics, School of Public Health, University of Washington, Seattle, WA, United States.ORCID 0000-0003-4995-238X
Brian E SaelensCenter for Child Health, Behavior and Development, Seattle Children's Research Institute, Seattle, WA, United States.ORCID 0000-0001-6998-6339

Funding

The Impact of Cerebral Metabolic Stress on the Development of the Structural and Functional Connectome in Pediatric Sickle Cell AnemiaR01HL157188 · NHLBI · WASHINGTON UNIVERSITY · PI FIELDS, MELANIE ERIN · 2021 to 2025
$3.1M
Are Interventions Supporting Physical ACtivity modified by the Environment (InSPACE)?R01HL157166 · NHLBI · SEATTLE CHILDREN'S HOSPITAL · PI SAELENS, BRIAN E · 2021 to 2024
$3.0M
NHLBI NIH HHS R01 HL157166NHLBI NIH HHS R01 HL157188
6 · The paper itself

Abstract

Background: Physical activity (PA) interventions can increase levels of PA to help participants meet recommended levels. The impact of PA interventions may be affected by an individual's neighborhood environment, including attributes such as walkability, crime rates, or greenspace availability, but research to date has lacked the power and geographic spread to adequately assess the role of the environment. Objective: The Interventions Supporting Physical Activity and the Environment (InSPACE) study used the Automatic Context Measurement Tool (ACMT) to gather environmental measures for participants around their home address in completed lifestyle intervention trials across the United States, then pooled and harmonized demographic and device-based activity data, creating a dataset for use in assessing the moderation effect of neighborhood attributes on interventions to increase PA. Methods: PA intervention trials were recruited from across the United States, and trialists were instructed in the use of the ACMT to geocode and collect prespecified environmental measures. The InSPACE research team gathered deidentified data from trialists, including demographics, raw accelerometry data, and ACMT-generated environmental measures and harmonized data to create a pooled dataset of PA intervention trial participants. Results: As of August 2025, a total of 39 PA intervention trials have been recruited and data from 31 of these trials have been processed and harmonized, creating a current pooled dataset of 4471 participants with any harmonized data, of whom 4360 (97.5%) have linked environmental data and 2208 (49.4%) have specified (3 days of at least 8 hours per day) accelerometry data for both baseline and postintervention. Results from the primary analysis for the InSPACE project are expected to be published in late 2026. Conclusions: InSPACE will contribute to understanding the role of the environment in moderating the effect of interventions to increase PA. The protocols and processes of InSPACE can inform future projects in pooled data harmonization and analysis.

Indexed as

EnvironmentExerciseAccelerometryHumansNeighborhood CharacteristicsRandomized Controlled Trials as TopicSecondary Data AnalysisUnited Statesaccelerometrybuilt environmentinterventionsphysical activityphysical activity interventionpooled analysissocial environment

Identifiers

PMID41569524
PMCPMC12826096

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.