Evidence map›Paper›PMID 41569453›Full record

Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026

The efficacy of complex decongestive therapy in the treatment of lymphedema associated with endometrial and cervical cancer: evaluation of sensation and balance.

Emine Cihan, Cansu Sahbaz Pirincci

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06204510 (Effects of Complex Decongestive Therapy on Proprioception, Balance and Tactile Sense in Lymphedema After Cancer Surgery), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06204510 naunknown statusnot on this map

Effects of Complex Decongestive Therapy on Proprioception, Balance and Tactile Sense in Lymphedema After Cancer Surgery: A Prospective Randomized Controlled Study

TypeinterventionalSponsorSelcuk UniversityRan2024 to 2024Enrolled40ConditionsLymphedema of Leg, Sensitisation, Balanced, Therapy-Associated CancerArmscomplex decongestive therapy
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Emine CihanDepartment of Therapy and Rehabilitation, Selcuk University, Vocational School of Health Sciences, Physiotherapy Program, Konya, Turkey. pteminecihan@gmail.com.ORCID http://orcid.org/0000-0003-0699-3771
Cansu Sahbaz PirincciGulhane Faculty of Physiotherapy and Rehabilitation, University of Health Sciences, Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to assess the impact of complex decongestive therapy (CDT) on proprioception, balance, light touch sensation, and two-point discrimination (2PD) in patients with lower extremity lymphedema (LLL) post-endometrial and cervical cancers.

methodsThe study included 72 patients diagnosed with LLL, who were randomly assigned using a block randomization method into two groups: a study group (n = 36) receiving CDT and a control group (n = 36) receiving no intervention. Patients were assessed before and after treatment using a digital goniometer for proprioception at 15°, 45°, and 60° knee flexion angles, a single-leg balance test with eyes open and closed, and a 30-s chair-stand test for balance assessment. Sensation was evaluated using Semmes Weinstein Monofilaments for light touch sensation and an aesthesiometer for 2PD.

resultsSignificant improvements were observed in knee flexion at 15°, 45°, and 60° in the study group compared to the control group (p < 0.001, p < 0.001, and p < 0.001, respectively). Although there was no difference between groups in single-leg balance with eyes open (p = 0.074) and closed (p = 0.919), improvements were noted within the study group before and after treatment (p < 0.001). There was no significant difference between groups in light touch sensation, while the 2PD parameter improved in the study group (p = 0.012).

conclusionsCDT may not fully address sensory deficits in patients with LLL. Balance issues appear to worsen with lymphedema progression regardless of treatment. However, CDT shows promise in improving kinesthesia. CLINICAL

trial registrationThis is listed with study ID: NCT06204510.

Indexed as

Endometrial NeoplasmsLymphedemaPostural BalanceUterine Cervical NeoplasmsAdultAgedFemaleHumansLower ExtremityMiddle AgedProprioceptionSensationBalanceKinesthesiaLight touch sensationLower extremity lymphedemaTwo-point discrimination

Identifiers

PMID41569453
PMCPMC12827376

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.