Evidence map›Paper›PMID 41569416›Full record

ArticleNeuroradiology2026

Success reperfusion remains a strong predictor of favourable outcome and reduced mortality in ischemic stroke patients with parenchymal haematoma post endovascular treatment: an international multi-centre cohort study.

Yimin Chen, Keng Siang Lee, Isabel Siow, Yibei Dai, Xiao Xiao, Apar Garg, Anil Gopinathan, Cunli Yang, Benjamin Yq Tan, Mingxue Jing and 16 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Neuroradiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

26 authors.

Yimin Chen *Nanfang Hospital, Southern Medical University, Guangzhou, China.
Keng Siang Lee *National Neuroscience Institute, Singapore, Singapore.
Isabel Siow *Ministry of Health Holdings, Singapore, Singapore. isabel.siow@yahoo.com.sg.
Yibei Dai *Nanfang Hospital, Southern Medical University, Guangzhou, China.
Xiao XiaoNational University Health System, Singapore, Singapore.
Apar GargNational University of Singapore, Singapore, Singapore.
Anil GopinathanNational University Health System, Singapore, Singapore.
Cunli YangWoodlands Health Campus, Singapore, Singapore.
Benjamin Yq TanNational University of Singapore, Singapore, Singapore.
Mingxue JingNational University of Singapore, Singapore, Singapore.
May ZinNational University Health System, Singapore, Singapore.
Hock Luen TeohNational University of Singapore, Singapore, Singapore.
Ching-Hui SiaNational University of Singapore, Singapore, Singapore.
Mingzhu FengFoshan Sanshui District People's Hospital, Foshan City, China.
Jicai MaThe Affiliated Yuebei People's Hospital of Shantou University Medical College, Shaoguan, China.
Lue ChenThe Eighth Affiliated Hospital of Southern Medical University, Foshan City, China.
Sijie ZhouFirst People's Hospital of Foshan, Foshan City, China.
Zunbao XuGuangzhou Medical University, Guangzhou, China.
Yongting ZhouHuadu District People's Hospital of Guangzhou, Guangzhou, China.
Yuzheng LaiGuangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Foshan City, China.
Wenhong PengShaoguan First People's Hospital, Shaoguan, China.
Yihua HeNanfang Hospital, Southern Medical University, Guangzhou, China.
Mohammad MofattehQueen's University Belfast, Belfast, United Kingdom.
Thanh N NguyenBoston University Chobanian & Avedisian School of Medicine, Boston, United States.
Suyue PanNanfang Hospital, Southern Medical University, Guangzhou, China. pansuyue@smu.edu.cn.
Leonard YeoNational University Health System, Singapore, Singapore. leonard_ll_yeo@nuhs.edu.sg.

Funding

National Medical Research Council NMRC MOH-001461Yong Loo Lin School of Medicine No.202409310004
6 · The paper itself

Abstract

introductionParenchymal haematoma (PH) is a potentially serious complication post endovascular treatment (EVT) and is associated with poor functional outcomes. It is unknown if modifiable factors can improve the outcomes of patients with PH. This study aimed to determine whether successful reperfusion is associated with favourable outcome in patients with ischemic stroke despite this complication.

methodsIn an international multi-centre study, favourable outcomes (mRS0-2) of patients achieving successful reperfusion (TICI 2b/3) were compared with outcomes of those with unsuccessful reperfusion.

results346 patients were included in the final analysis. 36 patients had unsuccessful reperfusion (10.4%) while 310 had successful reperfusion (89.6%). Amongst patients with PH post-EVT, successful reperfusion conferred better 3-month favourable outcomes (20.32% vs 5.56%; p=0.032) and lower mortality rates (40.32% vs 72.22%; p <0.001) compared with patients who had unsuccessful reperfusion.

conclusionSuccessful reperfusion remains a strong predictor of favourable outcome and reduced mortality in ischemic stroke patients with parenchymal haematoma post endovascular treatment.

Indexed as

Cerebral HemorrhageEndovascular ProceduresIschemic StrokePostoperative ComplicationsReperfusionAgedAged, 80 and overCohort StudiesFemaleHumansMaleMiddle AgedTreatment OutcomeBleedHaemorrhageReperfusionStrokeThrombectomy

Identifiers

PMID41569416

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