Evidence map›Paper›PMID 41569394›Full record

Trial reportMaternal & child nutrition2026

Caregiver Screening for Relapse Among Children Recently Recovered From Severe Acute Malnutrition: A Randomized Controlled Feasibility Trial.

Mamadou Bountogo, Clarisse Dah, Moussa Ouédraogo, Fanta Zerbo, Idrissa Kouanda, Elodie Lebas, Ian Fetterman, Jessica La Mons, Hadley Burroughs, Benjamin F Arnold and 2 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Maternal & child nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05932992 (Mother Screening for Relapse Using Mid-upper Arm Circumference Among Children Recovered From Severe Acute Malnutrition), which is not on this map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05932992 nacompletednot on this map

Mother Screening for Relapse Using Mid-upper Arm Circumference Among Children Recovered From Severe Acute Malnutrition

TypeinterventionalSponsorUniversity of California, San FranciscoRan2023 to 2024Enrolled400ConditionsSevere Acute MalnutritionArmsMother education on how to perform MUAC assessment
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mamadou BountogoCentre de Recherche en Santé de Nouna, Nouna, Burkina Faso.
Clarisse DahCentre de Recherche en Santé de Nouna, Nouna, Burkina Faso.
Moussa OuédraogoCentre de Recherche en Santé de Nouna, Nouna, Burkina Faso.
Fanta ZerboCentre de Recherche en Santé de Nouna, Nouna, Burkina Faso.
Idrissa KouandaCentre de Recherche en Santé de Nouna, Nouna, Burkina Faso.
Elodie LebasFrancis I Proctor Foundation, University of California, San Francisco, California, USA.
Ian FettermanFrancis I Proctor Foundation, University of California, San Francisco, California, USA.
Jessica La MonsDepartment of Ophthalmology, University of California, San Francisco, California, USA.
Hadley BurroughsDepartment of Ophthalmology, University of California, San Francisco, California, USA.
Benjamin F ArnoldFrancis I Proctor Foundation, University of California, San Francisco, California, USA.
Ali SiéCentre de Recherche en Santé de Nouna, Nouna, Burkina Faso.
Catherine E OldenburgFrancis I Proctor Foundation, University of California, San Francisco, California, USA.ORCID 0000-0002-0763-399X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Relapse to acute malnutrition after recovery from severe acute malnutrition (SAM) is common. However, most programmatic resources are devoted to the acute phase of recovery, and fewer interventions are available for children recently discharged from outpatient nutritional programs. We evaluated the feasibility of training caregivers to screen for relapse using mid-upper arm circumference (MUAC) tapes for reducing time to detection of relapse among children recently recovered from SAM in Burkina Faso. Caregiver-child dyads were enrolled and randomized in a 1:1 fashion to either caregiver MUAC screening or local standard of care (SOC), which consists of monthly clinic-based follow-up visits for 3 months following discharge. In the MUAC screening group, caregivers were trained on how to use a standard MUAC tape and asked to screen their child weekly with a provided MUAC tape for the 6-month duration of the study. The primary outcome was time to relapse detection, defined as MUAC < 12.5 cm and/or weight-for-height Z-score < -2. Secondary outcomes included hospitalization and/or death over the 6-month study period. Of 200 caregiver-child dyads enrolled in the trial, 99 were randomized to the MUAC screening group and 101 to the SOC group. By 6 months after enrollment, the hazard of relapse detection was lower in the MUAC screening group compared to the SOC group (hazard ratio, HR, 0.65, 95% confidence interval, CI, 0.38-1.12). Fewer hospitalizations and/or deaths occurred in the MUAC screening group compared to the SOC group (MUAC: 3%; SOC: 14%, risk ratio 0.23, 95% CI, 0.07-0.79). Training caregivers to screen for relapse after recovery from SAM was feasible and may lead to modestly reduced time to detection of relapse, suggesting a full-scale trial is warranted. Trial Registration: This study was prospectively registered on clinicaltrials.gov (NCT05932992, registered June 27, 2023).

Indexed as

CaregiversMass ScreeningSevere Acute MalnutritionAdultBurkina FasoChild, PreschoolFeasibility StudiesFemaleHumansInfantMaleRecurrencemid‐upper arm circumferencerandomized controlled trialscreeningsevere acute malnutrition

Identifiers

PMID41569394
PMCPMC12826110

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.