Evidence map›Paper›PMID 41569290›Full record

ArticleClinical oral investigations2026

Fully automatic AI diagnosis of alveolar bone defect in anterior teeth on CBCT images.

Runzhi Guo, Ning Ma, Tianlei Shi, Yufeng Wang, Qianyi Qin, Zining Chen, Feifei Zuo, Yajie Wang, Weiran Li

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Article in Clinical oral investigations, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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9 authors.

Runzhi Guo *Department of Orthodontics, Peking University School and Hospital of Stomatology, 22 Zhongguancun Avenue South, Haidian District, Beijing, 100081, P.R. China.
Ning Ma *Department of Stomatology, Peking University Third Hospital, Beijing, 100191, China.
Tianlei ShiLargeV Instrument Corp., Ltd., Beijing, 100084, China.
Yufeng WangLargeV Instrument Corp., Ltd., Beijing, 100084, China.
Qianyi QinDepartment of Orthodontics, Peking University School and Hospital of Stomatology, 22 Zhongguancun Avenue South, Haidian District, Beijing, 100081, P.R. China.
Zining ChenDepartment of Orthodontics, Peking University School and Hospital of Stomatology, 22 Zhongguancun Avenue South, Haidian District, Beijing, 100081, P.R. China.
Feifei ZuoLargeV Instrument Corp., Ltd., Beijing, 100084, China.
Yajie WangLargeV Instrument Corp., Ltd., Beijing, 100084, China. yj-wang18@mails.tsinghua.edu.cn.
Weiran LiDepartment of Orthodontics, Peking University School and Hospital of Stomatology, 22 Zhongguancun Avenue South, Haidian District, Beijing, 100081, P.R. China. weiranli@bjmu.edu.cn.

Funding

Beijing Natural Science Foundation L222114Beijing Natural Science Foundation L232026Beijing Natural Science Foundation L242129National Key Research and Development Program of China 2023YFC2413604
6 · The paper itself

Abstract

objectiveTo develop a fully automatic artificial intelligence (AI) system for diagnosing alveolar bone defects (ABDs) in anterior teeth on cone-beam computed tomography (CBCT) images. MATERIALS AND

methodsThis fully automatic AI system consists of two stages: (1) 2D image construction (sagittal and coronal slices) of anterior teeth root/bone morphology using a recognition algorithm, and (2) multi-perspective alveolar bone defect classification (normal, mild dehiscence, moderate dehiscence, severe dehiscence, and fenestration) based on the Hierarchical Multi-Scale Feature Fusion Network (HiFuse). In total, 300 CBCT images with 3600 anterior teeth from two clinical centers were used to train the model.

resultsThe system achieved automatic and accurate construction of sagittal and coronal slices for 12 anterior teeth, with a high structural similarity index measure (SSIM) index of 0.803. The HiFuse model significantly outperformed ConvNeXt and Swin Transformer counterparts (P < 0.05), achieving an accuracy of 0.936 (95% CI: 0.906-0.959), F1-score of 0.932 (95% CI: 0.895-0.955), recall of 0.936 (95% CI: 0.906-0.959), and precision of 0.928 (95% CI: 0.896-0.952). HiFuse also effectively distinguished between ABD types and accurately located alveolar bone defects.

conclusionsOur proposed AI system demonstrated great performance in ABDs diagnosis of anterior teeth using original 3D CBCT images and has potential for assisting with orthodontic diagnosis and decision-making. CLINICAL RELEVANCE: Accurate diagnosis of ABDs in anterior teeth is essential when selecting appropriate orthodontic treatment strategies and performing bone augmentation surgery. This AI system could preliminarily achieve diagnosis of ABDs in anterior teeth, reducing manual intervention and improving the overall diagnostic workflow.

Indexed as

Alveolar Bone LossArtificial IntelligenceCone-Beam Computed TomographyAlgorithmsHumansIntelligent SystemsAlveolar bone defectArtificial intelligenceCone-beam computed tomographyDentistryDiagnosisOrthodontics

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