ArticleAsian Pacific journal of cancer prevention : APJCP2026
Assessing the Role of Lifestyle in Modulating Serum IGF-1 and Association with Breast Cancer Risk among Palestinian Women in the Gaza Strip: A Case-Control Study.
Article in Asian Pacific journal of cancer prevention : APJCP, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBreast cancer (BC) continues to be one of the most commonly diagnosed cancers worldwide, predominantly affecting women. Insulin-like growth factor-1 (IGF-1) is vital for cellular growth and metabolism. Dysregulation of IGF-1 has been linked to an increased risk of cancer. We hypothesized that unhealthy lifestyle factors (e.g., poor diet, low physical activity) are associated with higher serum IGF-1 levels and an increased risk of BC. This research examines the relationship between lifestyle factors, IGF-1, and BC risk in Palestinian women in the Gaza Strip.
methodsA case-control study was conducted with 112 newly diagnosed BC women and 222 healthy controls. Data were collected using the International Physical Activity Questionnaire and the Food Frequency Questionnaire. IGF-1 levels were measured. Data were analyzed using SPSS version 28.
resultsBC patients had significantly lower physical activity than controls (58.9% vs. 44.6%, p = 0.014). Eight of the 14 food groups studied were linked to reduced BC risk, with reductions of 3.4% for fruit, 3.7% for meat, 5.6% for grains, 3.0% for low-fat dairy, 16.5% for nuts, 3.3% for snacks and sweets, and 5.5% for soups and sauces, while eggs increased risk by 12.5%. Drinks and beverages were positively correlated with IGF-1 levels (rp = 0.121, p = 0.027), suggesting that these factors may influence BC risk.
conclusionLifestyle factors, including diet and physical activity, influence IGF-1 levels and BC risk. Public health interventions promoting healthier lifestyles may help reduce BC risk.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.