Evidence map›Paper›PMID 41569109›Full record

ArticleMagnetic resonance in medicine2026

High-Resolution Diffusion-Weighted Imaging With Self-Gated Self-Supervised Unrolled Reconstruction.

Zhengguo Tan, Patrick A Liebig, Annika Hofmann, Frederik B Laun, Florian Knoll

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Combined ADC and TMagnetic resonance in medicine · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhengguo TanMichigan Institute for Imaging Technology and Translation (MIITT), Department of Radiology, University of Michigan, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0000-0002-4322-5109
Patrick A LiebigUltra-High Field Predevelopment Team, Siemens Healthcare GmbH, Erlangen, Bavaria, Germany.ORCID https://orcid.org/0000-0001-7342-3715
Annika HofmannArtificial Intelligence in Biomedical Engineering, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Bavaria, Germany.ORCID https://orcid.org/0009-0002-5723-1769
Frederik B LaunInstitute of Radiology, University Hospital Erlangen, Erlangen, Bavaria, Germany.ORCID https://orcid.org/0000-0002-9269-5609
Florian KnollArtificial Intelligence in Biomedical Engineering, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Bavaria, Germany.ORCID https://orcid.org/0000-0001-5357-8656

Funding

TR&D 4: Revealing Microstructure: Biophysical modeling and validation for discovery and clinical careP41EB017183 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Christopher M Collins · 2014 to 2026
$19.3M
Learning an Optimized Variational Network for Medical Image ReconstructionR01EB024532 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI JOHNSON, PATRICIA MARGARET, KNOLL, FLORIAN · 2018 to 2021
$1.8M
Deutsche Forschungsgemeinschaft 500888779Deutsche Forschungsgemeinschaft 512819079Deutsche Forschungsgemeinschaft 513220538NIH HHS P41EB017183NIH HHS R01EB024532
6 · The paper itself

Abstract

purposeHigh-resolution diffusion-weighted imaging (DWI) is clinically demanding. The purpose of this work is to develop an efficient self-supervised algorithm unrolling technique for submillimeter-resolution DWI.

methodsWe developed submillimeter DWI acquisition utilizing multi-band multi-shot EPI with diffusion shift encoding. We unrolled the alternating direction method of multipliers (ADMM) to perform scan-specific self-gated self-supervised DeepDWI learning for multi-shot echo planar imaging with diffusion shift encoding on a clinical 7 T scanner.

resultsWe demonstrate that (1) ADMM unrolling is generalizable across slices, (2) ADMM unrolling outperforms multiplexed sensitivity-encoding (MUSE) and compressed sensing with locally-low rank (LLR) regularization in terms of image sharpness, tissue continuity, and motion robustness, and (3) ADMM unrolling enables clinically feasible inference time.

conclusionOur proposed ADMM unrolling enables whole brain DWI of 21 diffusion volumes at 0.7 mm isotropic resolution and 10 min scan, and shows higher signal-to-noise ratio (SNR), clearer tissue delineation, and improved motion robustness, which makes it plausible for clinical translation.

Indexed as

BrainDiffusion Magnetic Resonance ImagingImage Processing, Computer-AssistedAlgorithmsEcho-Planar ImagingHumansalgorithm unrollingdiffusion weighted imagingimage reconstructionmachine learningself‐supervised learningsubmillimeter resolution

Identifiers

PMID41569109
PMCPMC12962217

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.