ArticleJournal of the American Heart Association2026
Comparing Clinical Outcomes of Patients With a Small Versus Large Annulus After Newer-Generation Balloon-Expandable Transcatheter Aortic Valve Replacement.
Article in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
18 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundLimited data are available comparing clinical outcomes between patients with small and large annuli following transcatheter aortic valve replacement using balloon-expandable valves. This study sought to investigate 5-year clinical outcomes in patients with severe aortic stenosis with a small annulus compared with those with a large annulus following transcatheter aortic valve replacement with newer-generation balloon-expandable valves.
methodsA total of 3182 patients with aortic stenosis treated with balloon-expandable valves were divided into small-annulus (≤430 mm
resultsAmong 533 matched pairs, compared with the large-annulus group, the small-annulus group had higher rates of aortic valve mean gradients ≥20 mm Hg (14.1% versus 2.9%;
conclusionsDespite higher transvalvular gradients and a greater rate of severe prosthesis-patient mismatch, 5-year clinical outcomes in patients with a small annulus were comparable to those with a large annulus following transcatheter aortic valve replacement using newer-generation balloon-expandable valves.
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