ArticleFrontiers in oncology2025
Adenoid basal carcinoma of the uterine cervix: a case report.
Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Adenoid basal carcinoma (ABC) is a rare human papillomavirus (HPV)-related malignancy of the uterine cervix that predominantly affects postmenopausal women, and it is a low-grade tumor with a favorable prognosis. This report presents a case of ABC along with a detailed immunohistochemical analysis. Case presentation: A 65-year-old woman tested positive for HPV types 16, 35, and 56 during routine screening. A subsequent cervical biopsy indicated adenocarcinoma. The patient was asymptomatic. She underwent radical hysterectomy, bilateral salpingo-oophorectomy, and bilateral pelvic lymph node dissection. A comprehensive pathological examination of the hysterectomy specimen confirmed ABC with a focal component of high-grade squamous intraepithelial lesion (HSIL). The postoperative course was uneventful, and no recurrence or metastasis was observed during 4 years of follow-up. Conclusion: Adequate tissue sampling and appropriate immunohistochemical profiling are valuable for accurate diagnosis and differentiation of ABC from other malignant cervical lesions.
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