Evidence map›Paper›PMID 41568343›Full record

ArticleCurrent research in food science2026

Tri-mode fluorescence/colorimetric/strip aptasensor with CRISPR/Cas12a-driven cascade strategy for mycotoxin.

Kan Yang, Changan Cheng, Youjia Zhang, Zhaoying Liu, Enze Sheng, Zhen Zhang, Ming Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current research in food science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kan YangSchool of the Environment and Safety Engineering, Jiangsu University, Zhenjiang, 212013, PR China.
Changan ChengSchool of the Environment and Safety Engineering, Jiangsu University, Zhenjiang, 212013, PR China.
Youjia ZhangSchool of the Environment and Safety Engineering, Jiangsu University, Zhenjiang, 212013, PR China.
Zhaoying LiuSchool of the Environment and Safety Engineering, Jiangsu University, Zhenjiang, 212013, PR China.
Enze ShengSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, PR China.
Zhen ZhangSchool of the Environment and Safety Engineering, Jiangsu University, Zhenjiang, 212013, PR China.
Ming LiSchool of the Environment and Safety Engineering, Jiangsu University, Zhenjiang, 212013, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multi-mode biosensors are promising rapid detection methods for mycotoxins, while these methods are still challenging in practice due to accessibility and efficiency. A tri-mode aptasensor platform based on CRISPR/Cas12a-driven cascade strategy is presented for ultrasensitive quantification of ochratoxin A (OTA) in this study. The probes of Apt@cDNA, fluorophore-quencher (FQ-reporter) and glucose oxidase (GOx)-reporter were prepared in advance to provide specific recognition and efficient signaling conversion. When target of OTA presented, the released cDNA aroused CHA reaction and then activated CRISPR/Cas12a, which not only used to turn-on the FQ-reporter but also release the GOx. To further improve the performance, the glucose was selected to generate numerous H

Indexed as

Cascade strategyCatalytic hairpin assemblyCRISPR-Cas12aOchratoxin ATri-mode aptasensor

Identifiers

PMID41568343
PMCPMC12818078

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.