ArticleFrontiers in surgery2025
Synergistic effect of early enteral and parenteral nutrition on immune and nutritional recovery following gastric cancer surgery.
Article in Frontiers in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: In this study, we aimed to explore the effects of early enteral nutrition (EN) combined with parenteral nutrition (PN) on the immune function and nutritional indices in patients with gastric cancer (GC) after surgery. Methods: A total of 100 patients who underwent radical gastrectomy in our hospital between June 2022 and June 2023 were selected and divided into control (CG) and observation (OG) groups. The patients in the CG received early EN support, whereas those in the OG received early EN combined with supportive PN treatment. Gastrointestinal functional recovery, length of hospital stay, nutritional indices, immune function, inflammatory stress index, and the incidence of complications in both groups were compared. Results: The time to first flatus, time to first defecation, time to tolerance of semi-liquid diet, and the length of hospital stay were shorter in the OG than that in the CG ( Conclusion: For patients with GC, the combined application of early EN and PN support measures after surgery can accelerate the recovery of gastrointestinal function, reduce complications, improve the body's nutritional status, promote the recovery of immune function, and lower the inflammatory stress response.
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