Evidence map›Paper›PMID 41568202›Full record

ArticlemedRxiv : the preprint server for health sciences2025

Evidence for Maternal Autoantibodies in the Pathogenesis of Preterm Birth.

Elze Rackaityte, Beltran Borges, Hannah M Kortbawi, Haleigh S Miller, Shirley J Shao, Kelsey C Zorn, Colette Caspar, Rebecca Wong, Frank McCarthy, Joseph S Creery and 39 more

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

49 authors.

Elze RackaityteDepartment of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA USA.ORCID 0000-0003-3889-8082
Beltran BorgesDepartment of Surgery, University of California San Francisco, San Francisco, CA USA.ORCID 0009-0004-6730-0398
Hannah M KortbawiDepartment of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA USA.ORCID 0000-0002-6482-0724
Haleigh S MillerDepartment of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA USA.ORCID 0000-0002-0920-7169
Shirley J ShaoDepartment of Obstetrics and Gynecology and Reproductive Sciences, University of California, San Francisco, CA USA.
Kelsey C ZornDepartment of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA USA.
Colette CasparDepartment of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.
Rebecca WongDepartment of Obstetrics and Gynecology and Reproductive Sciences, University of California, San Francisco, CA USA.
Frank McCarthyChan Zuckerberg Biohub San Francisco, San Francisco, CA, USA.
Joseph S CreeryChan Zuckerberg Biohub San Francisco, San Francisco, CA, USA.
Margareta MayerThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research.
Elaine KouameThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research.
Robert R PuccinelliUC Berkeley - UCSF Graduate Program in Bioengineering, University of California San Francisco, San Francisco, CA USA.
Amy L KistlerChan Zuckerberg Biohub San Francisco, San Francisco, CA, USA.
David J L YuDiabetes Center, School of Medicine, University of California San Francisco, San Francisco, CA USA.
Sammer Roach GanemDepartment of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA USA.
Alexandra DeRisiDepartment of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA USA.
Quinn KawajaDepartment of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA USA.
Chung-Yu WangChan Zuckerberg Biohub San Francisco, San Francisco, CA, USA.
Aditi SaxenaChan Zuckerberg Biohub San Francisco, San Francisco, CA, USA.
Scott OltmanDepartment of Epidemiology & Biostatistics, University of California San Francisco, San Francisco, CA USA.
Andrew F KungDepartment of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA USA.
Sabrina A MannDepartment of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA USA.
Anthea MitchellDepartment of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA USA.
David HuangDepartment of Obstetrics and Gynecology and Reproductive Sciences, University of California, San Francisco, CA USA.
Gabrielle RizzutoImmuno-Oncology Program and Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, NY, NY USA.
Rebecca J BaerDepartment of Epidemiology & Biostatistics, University of California San Francisco, San Francisco, CA USA.
Caleigh Mandel-BrehmDepartment of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA USA.
Kelli K RyckmanDepartment of Epidemiology and Biostatistics, School of Public Health-Bloomington, Indiana University, Bloomington, IN USA.
Stephanie L GawDepartment of Obstetrics and Gynecology and Reproductive Sciences, University of California, San Francisco, CA USA.
Sara L HillmanMaternal and Fetal Medicine Department, Institute for Women's Health, University College London, London, United Kingdom.
Laura L Jelliffe-PawlowskiDepartment of Epidemiology & Biostatistics, University of California San Francisco, San Francisco, CA USA.
Joanna HalkiasThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research.
Nasim C SobhaniDepartment of Obstetrics and Gynecology and Reproductive Sciences, University of California, San Francisco, CA USA.
Mark S AndersonDiabetes Center, School of Medicine, University of California San Francisco, San Francisco, CA USA.
Francsesca TrespidiHost-Pathogen Group and Neonatal Intensive Care Unit, IRCCS San Matteo Research Hospital, Pavia, Italy, EU.
Claudia AlpinLaboratory of Biochemical-Clinical Analyses, IRCCS San Matteo Research Hospital, Pavia, Italy, EU.
Tiziana BosoniLaboratory of Biochemical-Clinical Analyses, IRCCS San Matteo Research Hospital, Pavia, Italy, EU.
Riccardo AlbertiniLaboratory of Biochemical-Clinical Analyses, IRCCS San Matteo Research Hospital, Pavia, Italy, EU.
Camilla BellingeriDepartment of Obstetrics and Gynecology, IRCCS San Matteo Research Hospital, Pavia, Italy, EU.
Barbara GardellaDepartment of Obstetrics and Gynecology, IRCCS San Matteo Research Hospital, Pavia, Italy, EU.
Alessandro BorghesiHost-Pathogen Group and Neonatal Intensive Care Unit, IRCCS San Matteo Research Hospital, Pavia, Italy, EU.
Nicole PrinceChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Jessica Lasky-SuChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Michael R WilsonDepartment of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.
Marcelle CedarsDepartment of Obstetrics and Gynecology and Reproductive Sciences, University of California, San Francisco, CA USA.
Joshua E EliasChan Zuckerberg Biohub San Francisco, San Francisco, CA, USA.
Tippi C MacKenzieDepartment of Surgery, University of California San Francisco, San Francisco, CA USA.
Joseph L DeRisiDepartment of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA USA.

Funding

Investigating the role of maternal-fetal crosstalk on neonatal immunity in COVID-19 infection or vaccination in pregnancyR01HD111582 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Stephanie Lina Gaw · 2023 to 2026
$2.8M
Better utilization of omics data to inform precision medicine for asthma throughout the life courseR01HL169300 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI JESSICA A LASKY-SU · 2024 to 2026
$2.3M
Transdisciplinary Research Training to Reduce Disparities in Preterm Birth and Improve Maternal and Neonatal OutcomesT32HD098057 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KUPPERMANN, MIRIAM · 2019 to 2023
$1.4M
Maternal T cell recognition of placental antigenK08AI137209 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RIZZUTO, GABRIELLE A · 2018 to 2022
$1.0M
Placental malaria: The role of inflammation at the maternal-fetal interfaceK08AI141728 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GAW, STEPHANIE LINA · 2019 to 2023
$950k
Molecular understanding of maternal humoral responses to pregnancyK99AI182451 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RACKAITYTE, ELZE · 2024 to 2025
$247k
Molecular understanding of self immunity in the brainK99NS117800 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MANDEL-BREHM, CALEIGH · 2020 to 2021
$211k
Endometriosis autoantibody target discovery and functional validation.F30HD117526 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Hannah Kortbawi · 2025 to 2026
$89k
NHLBI NIH HHS R01 HL169300NIAID NIH HHS K08 AI137209NIAID NIH HHS K08 AI141728NIAID NIH HHS K99 AI182451NICHD NIH HHS F30 HD117526NICHD NIH HHS R01 HD111582NICHD NIH HHS T32 HD098057NINDS NIH HHS K99 NS117800
6 · The paper itself

Abstract

Complications from preterm birth are the leading cause of global mortality in children under age five

Identifiers

PMID41568202
PMCPMC12817887

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.