ArticleBrain, behavior, & immunity - health2026
Peripheral immune system activity in young psychiatry patients.
Article in Brain, behavior, & immunity - health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Infectious diseases and childhood disruptive behavior disorders: a reappraisal.Frontiers in cellular and infection microbiology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The interaction between the immune system and the central nervous system has been implicated in the development of psychiatric disorders in adult patients. However, comprehensive data regarding pediatric psychiatry are still lacking. This study aims to describe the distributions of various markers of immune system activity in a large clinical sample of children and adolescents and summarize the immunological profiles associated with different psychiatric disorders. We analyzed blood samples from 1543 patients aged 6-18 years (62 % female), admitted to the Child and Adolescent Psychiatry at the University Hospital of Tübingen between 2014 and 2024. Immune markers such as C-reactive protein and various cell counts and ratios were measured and regressed on psychiatric diagnoses according to the ICD-10 classification. Our findings revealed several distinct immunological profiles linked to specific psychiatric conditions in youth, such as higher CRP levels in patients with severe stress and adjustment disorders. The study underscores the potential role that immune system aberrations may play in mental health disorders and highlights the importance of investigating this link in this age group. However, some inconsistencies with the existing literature were found, such as the lack of association between depression and immune activity, which calls for further research to elucidate these relationships. Future studies should include longitudinal designs to better understand the causal pathways and potential for immune-targeted therapies in pediatric psychiatry.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.