Evidence map›Paper›PMID 41568067›Full record

ReviewBioMed research international2026

The Major Role of Type 2 Inflammation in Asthma: From the Perspective of Immunological Mechanism.

Lanying Cheng, Lihong Sun

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in BioMed research international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lanying ChengDepartment of Pediatric Pulmonology, The First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, Guangzhou, China, gzhmc.edu.cn.ORCID https://orcid.org/0009-0008-3017-5270
Lihong SunDepartment of Pediatric Pulmonology, The First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, Guangzhou, China, gzhmc.edu.cn.ORCID https://orcid.org/0000-0002-0495-8991

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asthma is a heterogeneous disease that affects individuals of diverse age groups globally and exhibits variable responses to different treatments. Type 2 inflammation contributes to the pathogenesis of asthma through the production of cytokines IL-4, IL-5, and IL-13, thereby inducing characteristic features of asthma such as elevated eosinophil levels and airway hyperresponsiveness. The findings of the current study indicate that over 50% of individuals suffering from asthma exhibit Type 2 inflammation, with a higher prevalence observed in severe asthma. Moreover, biologics specifically designed to target Type 2 inflammation not only demonstrate favorable outcomes in treating severe asthma but also offer promising prospects for managing this condition. Therefore, it is of paramount importance to comprehend the intricate mechanisms of Type 2 inflammation in asthma. This article is aimed at providing an overview of the involvement of structural cells, innate immune cells, and adaptive immune cells in relation to Type 2 inflammation in asthma.

Indexed as

AsthmaInflammationAnimalsCytokinesEosinophilsHumansImmunity, InnateInterleukin-13CytokinesInterleukin-13asthmaepithelial cellimmune cellsmechanismType 2 inflammation

Identifiers

PMID41568067
PMCPMC12817200

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.