Evidence map›Paper›PMID 41568035›Full record

ReviewFrontiers in microbiology2025

Mapping antibiotic resistance in Ghana: a narrative review of regional variations in antibiotic-resistant ESKAPEE pathogens.

Abdulwasid Abubakari, Rosemary Agbeko, George Osei-Adjei, Rolf Kümmerli

Abstract readReview
In one paragraph

Review in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Abdulwasid AbubakariDepartment of Science Laboratory Technology, Accra Technical University, Accra, Ghana.
Rosemary AgbekoDepartment of Biochemistry, School of Biological Sciences, College of Agriculture and Natural Sciences, University of Cape Coast, Cape Coast, Ghana.
George Osei-AdjeiDepartment of Science Laboratory Technology, Accra Technical University, Accra, Ghana.
Rolf KümmerliDepartment of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Antibiotic resistance (ABR) is a global health crisis and a significant public health challenge in Ghana. This narrative review aims to uncover the patterned landscape of ABR by systematically assessing regional heterogeneity across three key dimensions: (1) the geographic distribution and intensity of ABR surveillance and research; (2) the prevalence of ESKAPEE pathogens ( Methods: Four online databases (PubMed, Scopus, Web of Science, and African Journals Online) were searched for relevant articles published from 2016 to 2025, a timeframe chosen to align with the development and implementation of Ghana's first National Action Plan (NAP) on AMR (2017-2021). A narrative synthesis was conducted to collate, analyze, and map regional data on ESKAPEE pathogen prevalence, resistance patterns, and underlying genetic mechanisms. Results: A total of 48 studies met the inclusion criteria. The findings reveal a significant disparity in research coverage, with a heavy concentration of studies in the Greater Accra (35.4%) and Ashanti (18.6%) regions. Widespread multidrug resistance was evident across all studied regions, with Conclusion: ABR in Ghana presents as a patterned landscape rather than a uniform national profile. Stark regional disparities and major surveillance gaps create "blind spots" that can hinder the effective implementation of national policy. Addressing this requires prioritizing surveillance in under-studied regions and standardizing methodologies. Furthermore, region-specific control strategies must be developed using a "One Health" approach, one that integrates surveillance and stewardship interventions across human healthcare, agricultural, and environmental sectors.

Indexed as

antimicrobial resistanceESKAPEE pathogensGhanaOne Healthregional heterogeneitysurveillance

Identifiers

PMID41568035
PMCPMC12816315

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.