Evidence map›Paper›PMID 41568034›Full record

ArticleFrontiers in microbiology2025

Gene and function diversity-area relationships in the inflammatory bowel disease fecal and mucosal microbiome.

Fubing Yu, Jiyang Song, Linyi Qi, Jinghua Liu, Yintiantian Yang, Wendy Li, Lianwei Li, Zhanshan Sam Ma

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fubing Yu *Department of Gastroenterology, Affiliated Hospital of Yunnan University, Kunming, China.
Jiyang Song *Department of Cardiology, Gansu Provincial Hospital, Lanzhou, Gansu, China.
Linyi QiInstitute of Medical Biology, Chinese Academy of Medical Sciences, Kunming, China.
Jinghua LiuDepartment of Gastroenterology, Affiliated Hospital of Yunnan University, Kunming, China.
Yintiantian YangDepartment of Gastroenterology, Affiliated Hospital of Yunnan University, Kunming, China.
Wendy LiCollege of Biological Sciences and Technology, Taiyuan Normal University, Jinzhong, China.
Lianwei LiMicrobiome Medicine and Advanced AI Technology, Kunming, China.
Zhanshan Sam MaMicrobiome Medicine and Advanced AI Technology, Kunming, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The diversity-area relationship (DAR), an extension of the classic species-area relationship (SAR), provides a powerful framework for understanding how biodiversity scales across space. In this study, we applied DAR and its metagenomic counterpart (m-DAR) to investigate the spatial scaling of metagenomic genes (MGs) and metagenomic functional gene clusters (MFGCs) of seven functional databases in the gut microbiomes of individuals with inflammatory bowel disease (IBD) and healthy cohorts. Using shotgun sequencing data from 42 mucosal and 22 fecal samples from both healthy and IBD cohorts, we modeled how this MGs and MFGCs accrues with area (samples), estimating diversity scaling parameters (

Indexed as

diversity-area relationship (DAR)inflammatory bowel disease (IBD)maximal accrual diversity (MAD)metagenomic functional gene clusters (MFGCs)metagenomic genes (MGs)

Identifiers

PMID41568034
PMCPMC12815819

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.