Evidence map›Paper›PMID 41567945›Full record

ArticleAfrican journal of laboratory medicine2025

Odilon D Kaboré, Mélissa J Gonfouli, Merci Muhigwa, Abdourahmane Sow, Fernand Michodigni, André Nagalo, Jacques Zoungrana, Arsène Hema, Augustin Konkobo, Hervé Kafando and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in African journal of laboratory medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Odilon D KaboréLaboratory of Bacteriology and Virology, Sourô Sanou University Teaching Hospital, Bobo-Dioulasso, Burkina Faso.ORCID https://orcid.org/0000-0001-8737-4555
Mélissa J GonfouliLaboratory of Emerging and Re-emerging Pathogens, School of Health Sciences, Nazi Boni University, Bobo-Dioulasso, Burkina Faso.ORCID https://orcid.org/0000-0002-6057-8328
Merci MuhigwaLaboratory of Emerging and Re-emerging Pathogens, School of Health Sciences, Nazi Boni University, Bobo-Dioulasso, Burkina Faso.ORCID https://orcid.org/0000-0002-0311-3292
Abdourahmane SowRegion Wide Laboratory Services, West African Health Organization, Bobo-Dioulasso, Burkina Faso.ORCID https://orcid.org/0000-0002-0197-5817
Fernand MichodigniLaboratory of Emerging and Re-emerging Pathogens, School of Health Sciences, Nazi Boni University, Bobo-Dioulasso, Burkina Faso.ORCID https://orcid.org/0000-0003-2304-2601
André NagaloLaboratory of Emerging and Re-emerging Pathogens, School of Health Sciences, Nazi Boni University, Bobo-Dioulasso, Burkina Faso.ORCID https://orcid.org/0000-0002-7862-7634
Jacques ZoungranaLaboratory of Emerging and Re-emerging Pathogens, School of Health Sciences, Nazi Boni University, Bobo-Dioulasso, Burkina Faso.ORCID https://orcid.org/0000-0002-9397-5901
Arsène HemaDepartment of Quality, Sourô Sanou University Teaching Hospital, Bobo-Dioulasso, Burkina Faso.ORCID https://orcid.org/0000-0002-5279-643X
Augustin KonkoboLaboratory of Emerging and Re-emerging Pathogens, School of Health Sciences, Nazi Boni University, Bobo-Dioulasso, Burkina Faso.ORCID https://orcid.org/0000-0001-9593-1534
Hervé KafandoLaboratory of Emerging and Re-emerging Pathogens, School of Health Sciences, Nazi Boni University, Bobo-Dioulasso, Burkina Faso.ORCID https://orcid.org/0000-0002-8136-1486
Adama OuattaraHigher Institute of Health Sciences, Nazi Boni University, Bobo-Dioulasso, Burkina Faso.ORCID https://orcid.org/0000-0001-8910-0806
Armel PodaLaboratory of Emerging and Re-emerging Pathogens, School of Health Sciences, Nazi Boni University, Bobo-Dioulasso, Burkina Faso.ORCID https://orcid.org/0000-0002-7463-9179
Sylvain GodreuilJoint Research Unit, Research Institute for Development, National Center for Scientific Research, Inserm, Faculty of Infectious Diseases and Vectors: Ecology, Genetics, Evolution and Control, University of Montpellier, Montpellier, France.ORCID https://orcid.org/0000-0003-3436-0082
Abdoul-Salam OuedraogoLaboratory of Bacteriology and Virology, Sourô Sanou University Teaching Hospital, Bobo-Dioulasso, Burkina Faso.ORCID https://orcid.org/0000-0002-8539-3768

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Tigecycline, an antibiotic effective against multidrug-resistant bacteria (MDRB), remains inaccessible in Burkina Faso's hospitals for urgent care. Given the resulting therapeutic challenges and mortality in emergency services, evidence-based study of tigecycline's efficacy on local bacterial clinical isolates is necessary before recommending its use. Objective: This study aimed to evaluate the activity of tigecycline on MDRB isolates at the Sourô Sanou University Teaching Hospital laboratory, Burkina Faso. Methods: This was a cross-sectional study with prospective and consecutive sampling of MDRBs. The latter included extended-spectrum Results: A total of 117 MDRBs, including 93 Enterobacterales, 15 carbapenem-resistant Conclusion: The activity of tigecycline was highly effective on ESBL-E, carbapenem resistant Enterobacterales and MRSA, and moderate on What this study adds: This was the first report on the evaluation of tigecycline activity on MDRBs in Burkina Faso. This non-marketed antibiotic in Burkina Faso could represent an alternative to spare carbapenems in the treatment of ESBL-E infections, and a last resort antibiotic against susceptible CRS infections in Burkina Faso's hospitals.

Indexed as

Acinetobacter baumanniiBurkina FasoEnterobacteralesextended-spectrum β-lactamase-producing Enterobacteralesin vitromethicillin-resistant Staphylococcus aureusmultidrug-resistant bacteriatigecycline

Identifiers

PMID41567945
PMCPMC12817021

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.