Evidence map›Paper›PMID 41567824›Full record

ArticleNeurobiology of stress2026

Central amygdala

Luisa B Bertotto, Eleanna M Sakoulas, Marian L Logrip, Katrina Lin, Anastasia E Pimentel, Lenwood Thompson, Bryan Cruz, Valentina Vozella, Cristiane A Favoretto, Marisa Roberto and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurobiology of stress, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Luisa B BertottoDepartment of Translational Medicine, The Scripps Research Institute, La Jolla, CA, 92093, USA.
Eleanna M SakoulasDepartment of Translational Medicine, The Scripps Research Institute, La Jolla, CA, 92093, USA.
Marian L LogripDepartment of Psychology, Indiana University Indianapolis, Indianapolis, IN, 46202, USA.
Katrina LinDepartment of Translational Medicine, The Scripps Research Institute, La Jolla, CA, 92093, USA.
Anastasia E PimentelDepartment of Translational Medicine, The Scripps Research Institute, La Jolla, CA, 92093, USA.
Lenwood ThompsonDepartment of Translational Medicine, The Scripps Research Institute, La Jolla, CA, 92093, USA.
Bryan CruzDepartment of Translational Medicine, The Scripps Research Institute, La Jolla, CA, 92093, USA.
Valentina VozellaDepartment of Translational Medicine, The Scripps Research Institute, La Jolla, CA, 92093, USA.
Cristiane A FavorettoDepartment of Translational Medicine, The Scripps Research Institute, La Jolla, CA, 92093, USA.
Marisa RobertoDepartment of Translational Medicine, The Scripps Research Institute, La Jolla, CA, 92093, USA.
Eric P ZorrillaDepartment of Translational Medicine, The Scripps Research Institute, La Jolla, CA, 92093, USA.

Funding

Synaptic Mechanisms underlying sex-differences in alcohol use disorderR01AA029841 · NIAAA · SCRIPPS RESEARCH INSTITUTE, THE · PI MARISA ROBERTO · 2022 to 2026
$2.0M
Extended amygdala somatostatin role in post-traumatic stress and alcohol use disorderK99AA031718 · NIAAA · SCRIPPS RESEARCH INSTITUTE, THE · PI CRUZ, BRYAN · 2024 to 2025
$361k
NIAAA NIH HHS K99 AA031718NIAAA NIH HHS R01 AA029841
6 · The paper itself

Abstract

Stress-related emotional disorders, such as post-traumatic stress disorder (PTSD) and major depression, increase alcohol relapse risk. PTSD, depression, and alcohol use phenotypes associate with gene variants of FKBP prolyl isomerase 5 (

Indexed as

Benztropine or cogentinCentral nucleus of the amygdalaCorticosteroid receptorEthanol or alcohol use disorderFK506-Binding protein 51 or FKBP51FosFosBRelapseSex differenceSocial defeat or foot-shock stressΔFosb immediate-early genes

Identifiers

PMID41567824
PMCPMC12818279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.