ArticleAdvances in geriatric medicine and research2025
From First Slip to Second Setback: Intracranial Injury Risk after Recurrent Falls in Older Adults: A Retrospective Cohort Study.
Article in Advances in geriatric medicine and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Recurrent falls in older adults are a major public health concern, often resulting in severe injuries such as Intracranial Injuries (ICIs). These injuries increase the risk of cognitive decline, disability, and early mortality. While medications like antihypertensives and antidepressants are essential for managing chronic conditions, they may also contribute to fall-related injury risk. Methods: This retrospective cohort study analyzed data from 3760 adults aged 65 to 89 years at the Virginia Commonwealth University Health System (VCUHS) in 2023. Patients were categorized into two cohorts: those with initial falls ( Results: The risk of ICI was 10.4% higher in patients with recurrent falls compared to those with initial falls (HR = 1.104, 95% CI: 0.833-1.463, Conclusions: Recurrent falls were associated with a higher likelihood of ICIs among older adults, particularly in males, those of advanced age, and individuals prescribed antihypertensive or antidepressant medications. These results point to the importance of identifying patients at increased vulnerability and tailoring fall-related care and medication reviews accordingly to help reduce injury severity in this population.
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