Evidence map›Paper›PMID 41567771›Full record

ArticleFrontiers in public health2025

The theoretical impact of AI-based quality evaluation of short-video health information on public cognition and treatment adherence: a case study of denosumab combined with PD-1/PD-L1 therapy for lung cancer bone metastasis.

Jia-Wen Wang, Jian-Jun Xun, Fei-Fei Zhao

Abstract read
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Jia-Wen WangDepartment of Orthopedics, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Jian-Jun XunDepartment of Orthopedics, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Fei-Fei ZhaoDepartment of Orthopedics, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Bone metastasis occurs in 30-40% of patients with advanced non-small cell lung cancer (NSCLC), and denosumab combined with PD-1/PD-L1 inhibitors has emerged as a promising treatment strategy. However, the "algorithmic echo chamber" effect on short-video platforms may distort patient cognition and treatment decision-making. Methods: A cross-sectional study was conducted using a custom-developed web crawler to collect 1,369 videos from Bilibili, Douyin, and Xiaohongshu. A total of 402 videos were included after a three-tier keyword filtering process. An AI-based evaluation system built upon the doubao-seed-1.6 model was established, integrating three international standards-Global Quality Score (GQS), Journal of the American Medical Association (JAMA) benchmark criteria, and the modified DISCERN tool-to assess multidimensional information quality. Kruskal-Wallis tests and Spearman correlation analyses were performed to explore inter-platform differences and the relationship between information quality and user engagement metrics. Results: Overall video quality was substantially below professional medical standards: the mean GQS was 2.84 ± 1.06 (56.8% of the full score), JAMA was 0.34 ± 0.57 (8.5%), and modified DISCERN was 1.55 ± 0.69 (31.0%). Significant quality differences were observed across platforms ( Conclusion: From a behavioral and cognitive perspective, the low quality of immune-oncology information on short-video platforms, coupled with algorithm-driven amplification of high-engagement but low-quality content, may exacerbate cognitive bias, potentially increasing clinical safety risks such as insufficient hypocalcemia monitoring and inadequate MRONJ prevention. Establishing a professional governance and oversight system is urgently required.

Indexed as

Artificial IntelligenceBone NeoplasmsCarcinoma, Non-Small-Cell LungCognitionConsumer Health InformationDenosumabImmune Checkpoint InhibitorsLung NeoplasmsVideo RecordingB7-H1 AntigenCross-Sectional StudiesHumansProgrammed Cell Death 1 ReceptorB7-H1 AntigenDenosumabImmune Checkpoint InhibitorsProgrammed Cell Death 1 ReceptorAI evaluationalgorithmic echo chambercognitive biasdenosumabhealth information qualityimmune checkpoint inhibitorslung cancer bone metastasisshort-video platforms

Identifiers

PMID41567771
PMCPMC12816342

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.