ArticleFrontiers in medicine2025
Relationship between different blood routine parameters and different types of sudden deafness and prognosis.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Diabetes Mellitus as a Risk Factor in Recurrent Vestibular Disorders: An Update.Audiology research · 2026Review
- Novel Systemic Inflammatory Indices (SII and SIRI) as Mediators Between BMI and Hearing Loss.Mediators of inflammation · 2026Article
- Serum ENA-78, CXCL1, and caspase-3 are associated with disease severity and early hearing recovery in idiopathic sudden sensorineural hearing loss.Frontiers in neuroscience · 2026Article
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Authors and funding
4 authors.
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Abstract
This retrospective observational analysis examined the relationship between blood routine parameters and audiometric subtypes of sudden sensorineural hearing loss and prognosis. The 379 participants were then divided into groups according to audiometric configuration, time of onset of symptoms, and prognosis at 4 weeks after therapy. Hemoglobin, neutrophilia, lymphopenia, monocytosis, thrombocytosis, and hypoalbuminemia were positively associated with prognosis, while lymphocytosis, platelet count, age, gender, ASA physical status, obesity, chronic illnesses, chronic kidney disease, diabetes mellitus, hypertension, dyslipidemia, and smoking were inversely associated. The independent predictive biomarker was identified as neutrophil to lymphocyte ratio after adjusting for the other indices, such as C-reactive protein and erythrocyte sedimentation rate. Finally, we examined the relationships between the recovery prognosis and symptom onset time, corticosteroid use, and hearing loss. The results have highlighted that a combined assessment with hematological and inflammatory markers will provide better prognosis prediction and enhance the SSNHL treatment approaches.
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