Evidence map›Paper›PMID 41567586›Full record

ArticleBJUI compass2026

Effect of tranexamic acid irrigation on perioperative blood loss during mini-percutaneous nephrolithotomy: A pilot double-blind randomised controlled trial.

Ornnicha Prohsoontorn, Kun Sirisopana, Surawach Piyawannarat, Yada Phengsalae, Premsant Sangkum, Wisoot Kongchareonsombat, Chinnakhet Ketsuwan

Abstract read
In one paragraph

Article in BJUI compass, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ornnicha ProhsoontornDivision of Urology, Department of Surgery, Faculty of Medicine Ramathibodi Hospital Mahidol University Bangkok Thailand.
Kun SirisopanaDivision of Urology, Department of Surgery, Faculty of Medicine Ramathibodi Hospital Mahidol University Bangkok Thailand.ORCID https://orcid.org/0000-0001-7976-2929
Surawach PiyawannaratDivision of Urology, Department of Surgery, Faculty of Medicine Ramathibodi Hospital Mahidol University Bangkok Thailand.
Yada PhengsalaeDivision of Urology, Department of Surgery, Faculty of Medicine Ramathibodi Hospital Mahidol University Bangkok Thailand.
Premsant SangkumDivision of Urology, Department of Surgery, Faculty of Medicine Ramathibodi Hospital Mahidol University Bangkok Thailand.
Wisoot KongchareonsombatDivision of Urology, Department of Surgery, Faculty of Medicine Ramathibodi Hospital Mahidol University Bangkok Thailand.
Chinnakhet KetsuwanDivision of Urology, Department of Surgery, Faculty of Medicine Ramathibodi Hospital Mahidol University Bangkok Thailand.ORCID https://orcid.org/0000-0002-0667-8619

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the efficacy and safety of adding 0.1% tranexamic acid (TXA) to irrigation fluid in reducing perioperative blood loss during mini-percutaneous nephrolithotomy (mini-PCNL). Patients and Methods: In this prospective, randomised study, 40 patients undergoing mini-PCNL were allocated to receive irrigation fluid containing either 0.1% TXA ( Results: Baseline characteristics were comparable between the two groups. The TXA group had significantly less haemoglobin decline (0.5 g/dl vs. 1.5 g/dl) and lower estimated blood loss (91.7 ml vs. 169.0 ml) compared with the placebo group (both Conclusion: The addition of 0.1% TXA to irrigation fluid during mini-PCNL significantly reduces perioperative blood loss and appears to be safe in this pilot cohort, without increasing complications observed in the study.

Indexed as

blood lossirrigationmini‐PCNLtopical administrationtranexamic acid

Identifiers

PMID41567586
PMCPMC12819009

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.