Evidence map›Paper›PMID 41567486›Full record

ArticleTurkish journal of emergency medicine

First use of andexanet alfa in the management of massive delayed hemothorax.

Miroslaw Kozlowski, Julia Antkiewicz, Anna Choroszewska, Krystian Czolpinski, Pawel Niemynski

Abstract readCase Reports
In one paragraph

Article in Turkish journal of emergency medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Miroslaw KozlowskiDepartment of Thoracic Surgery, Medical University of Bialystok, Białystok, Poland.ORCID https://orcid.org/0000-0003-4563-2135
Julia AntkiewiczDepartment of Thoracic Surgery, Students' Scientific Group, Medical University of Bialystok, Białystok, Poland.ORCID https://orcid.org/0009-0008-8651-6679
Anna ChoroszewskaDepartment of Thoracic Surgery, Students' Scientific Group, Medical University of Bialystok, Białystok, Poland.ORCID https://orcid.org/0009-0005-2253-9175
Krystian CzolpinskiDepartment of Thoracic Surgery, Students' Scientific Group, Medical University of Bialystok, Białystok, Poland.ORCID https://orcid.org/0009-0009-1133-5889
Pawel NiemynskiDepartment of Thoracic Surgery, Medical University of Bialystok, Białystok, Poland.ORCID https://orcid.org/0009-0002-8534-5130

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In emergency medicine practice, massive hemothorax represents a life-threatening condition in patients with comorbidities. We present the case of a 75-year-old female patient with a massive delayed hemothorax, which developed following a chest injury sustained during a low-height fall. The patient had been on long-term rivaroxaban, a direct oral anticoagulant, due to underlying comorbid conditions. To reverse the anticoagulant effect, andexanet alfa was administered, followed by the placement of chest drainage. After evacuating the bloody pleural effusion from the pleural cavity, full lung reexpansion was achieved, with only minimal residual drainage within an hour. Following drainage removal, the patient was subsequently discharged without any complications. After follow-up, the patient remained in good condition. This case demonstrates that andexanet alfa can be an effective reversal agent in life-threatening cases of massive delayed hemothorax.

Indexed as

Andexanet alfadelayed hemothoraxmassive hemothorax

Identifiers

PMID41567486
PMCPMC12818778

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.