ArticleTurkish journal of emergency medicine
Sepsis-induced coagulopathy and its association with mortality in patients with sepsis and septic shock.
Article in Turkish journal of emergency medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Role of Thromboelastometry in Sepsis-Induced Coagulopathy: A Narrative Review.Medical sciences (Basel, Switzerland) · 2026Review
- Prognostic Value of International Normalized Ratio and Thrombocytopenia in Early Risk Stratification of Septic Patients.Biomedicines · 2026Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesSepsis-induced coagulopathy (SIC) is a common complication in patients with sepsis and septic shock. Early detection of SIC is crucial for timely intervention, as it can significantly impact patient outcomes. This study aims to evaluate the prevalence of SIC and its impact on the 28-day mortality rate in patients with sepsis and septic shock.
methodsA single-center retrospective observational cohort study was conducted in Vietnam from January 2021 to August 2024. Adult patients diagnosed with sepsis or septic shock who were admitted to the intensive care unit within 24 h of initial presentation were included. Patients with do-not-resuscitate orders, coagulopathy, malignant blood disorders, incomplete data, or refusal of treatment were excluded. SIC scores were assessed, and 28-day mortality rates were recorded.
resultsA total of 340 patients were included, with 216 (63.5%) exhibiting SIC (SIC score ≥4). The mean age of patients was 69.01 ± 17.04 years, and the majority were male (61.5%). Septic shock accounted for 79.7% of the cases. SIC patients had significantly higher mortality rates at both 4 days (17.6% vs. 4.8%,
conclusionsThe prevalence of SIC is high in patients with sepsis and septic shock, especially in our cohorts. SIC score ≥4 is also a strong and independent predictor for 28-day mortality.
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