ArticleFrontiers in pediatrics2025
Evaluation of near-infrared spectroscopy, transcranial Doppler, and ophthalmic ultrasound measurements in critically Ill pediatric patients with increased intracranial pressure.
Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Association Between Pain, Agitation, and Intracranial Pressure with Cerebral Near-Infrared Spectroscopy in Critically Ill Children: A Prospective Pilot Study.Journal of clinical medicine · 2026Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: Non-invasive methods are needed to rapidly assess increased ICP, especially for managing patients when invasive devices are unavailable or contraindicated. This study aims to examine the diagnostic value of transcranial Doppler (TCD), ophthalmic ultrasound measurements, and near-infrared spectroscopy (NIRS) to define non-invasive ICP (nICP) in the evaluation of pediatric intensive care unit (PICU) patients with increased ICP. Methods: This is a Single center prospective case-control study. The study group comprised 32 pediatric patients with increased ICP, while the control group comprised 64 healthy children. The following non-invasive methods were measured prospectively: optic nerve sheath diameter (ONSD)-derived nICP (nICPONSD), central retinal artery Doppler indices, arterial TCD blood velocities, pulsatility index (PI)-derived nICP (nICPPI), Lindegaard ratio (L/R), and NIRS values. Results: Mean ONSD, retinal artery resistive index (RI), middle cerebral artery (MCA) RI, nICPONSD, and L/R were significantly greater in the study group than the control group ( Conclusion: The availability and utilization of both TCD and ophthalmic ultrasound methods have recently increased. This is the first pediatric report that focuses on comparing ONSD, TCD, and NIRS and evaluates the Doppler indices in patients with increased ICP.
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