Evidence map›Paper›PMID 41567387›Full record

ArticleFrontiers in cardiovascular medicine2025

Factors influencing postoperative hyperbilirubinemia in valvular heart disease and establishment of a predictive model.

Chenchen Cheng, Haiping Wang, Baoguo Zhou, Zhenqian Lv, Xiaojun Liu, Gang Wang, Yan Qiao

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Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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7 authors.

Chenchen ChengDepartment of Cardiovascular Surgery, Qingdao Cardiovascular Hospital, Qingdao, Shandong, China.
Haiping WangDepartment of Cardiovascular Surgery, Qingdao Cardiovascular Hospital, Qingdao, Shandong, China.
Baoguo ZhouDepartment of Cardiovascular Surgery, Qingdao Cardiovascular Hospital, Qingdao, Shandong, China.
Zhenqian LvDepartment of Cardiovascular Surgery, Qingdao Cardiovascular Hospital, Qingdao, Shandong, China.
Xiaojun LiuDepartment of Cardiovascular Surgery, Qingdao Cardiovascular Hospital, Qingdao, Shandong, China.
Gang WangDepartment of Cardiovascular Surgery, Qingdao Cardiovascular Hospital, Qingdao, Shandong, China.
Yan QiaoDepartment of Cardiovascular Surgery, Qingdao Cardiovascular Hospital, Qingdao, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: To explore the influencing factors of postoperative hyperbilirubinemia (HB) in patients with valvular heart disease (VHD) and establish a predictive model based on these factors. Methods: Clinical data of VHD patients who underwent surgical treatment in Qingdao Cardiovascular Hospital from March 2022 to February 2024 were retrospectively collected. The patients were divided into a modeling group ( Results: The results of multivariable logistic regression analysis showed that the type of surgery (OR = 4.959, 95% CI: 2.592-9.487), preoperative MELD score (OR = 4.332, 95% CI: 2.061-9.105), CPB time (OR = 3.851, 95% CI: 1.591-9.321), aortic cross-clamp time (OR = 3.667, 95% CI: 1.521-8.841), intraoperative total blood transfusion volume (OR = 4.125, 95% CI: 1.982-8.586), and mechanical ventilation time (OR = 4.089, 95% CI: 2.000-8.362) were risk factors for the occurrence of HB in the modeling group ( Conclusion: The type of surgery, preoperative MELD score, CPB time, aortic cross-clamp time, intraoperative total blood transfusion volume, and mechanical ventilation time are risk factors for the occurrence of HB in patients with VHD. The nomogram model constructed based on these risk factors has good predictive value and accuracy.

Indexed as

hyperbilirubinemiapredictive modelrisk factorsvalvular heart diseaseVHD

Identifiers

PMID41567387
PMCPMC12816281

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